Giant cell tumor of bone: a basic science perspective
Comprehending the pathogenesis of giant cell tumor of bone (GCT) is of critical importance
for develo** novel targeted treatments for this locally-aggressive primary bone tumor. GCT …
for develo** novel targeted treatments for this locally-aggressive primary bone tumor. GCT …
MiR-126-5p regulates osteoclast differentiation and bone resorption in giant cell tumor through inhibition of MMP-13
Z Wu, H Yin, T Liu, W Yan, Z Li, J Chen, H Chen… - Biochemical and …, 2014 - Elsevier
Giant cell tumor (GCT) of bone is an aggressive skeletal tumor characterized by localized
bone resorption. Matrix metalloproteinase-13 (MMP-13) is the principal proteinase …
bone resorption. Matrix metalloproteinase-13 (MMP-13) is the principal proteinase …
MiR-126-5p regulates osteolysis formation and stromal cell proliferation in giant cell tumor through inhibition of PTHrP
W Zhou, H Yin, T Wang, T Liu, Z Li, W Yan, D Song… - Bone, 2014 - Elsevier
Parathyroid hormone-related protein (PTHrP) has been identified to play a crucial role in
osteolysis formation and stromal cell (GCTSC) proliferation in giant cell tumor (GCT). MiR …
osteolysis formation and stromal cell (GCTSC) proliferation in giant cell tumor (GCT). MiR …