Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset
of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their …

Inflammation is a biological response of the immune system to various insults, such as
pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro …

Over the past few decades, substantial evidence has convincingly revealed the existence of
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …

Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

INTRODUCTION Recently, a special class of RNAs has excited researchers and triggered
hundreds of now-published studies. Known as circular RNAs (circRNAs), these RNAs are …

Purpose: Colorectal cancer is one of the most common malignancies worldwide. Recently, a
novel circular RNA, ciRS-7, was proposed to be a potential miR-7 sponge. As miR-7, a …

Metastasis accounts for 90% of breast cancer mortality. Despite the significant progress
made over the past decade in cancer medicine our understanding of metastasis remains …

Up to 30% of patients with metastatic breast cancer eventually develop brain metastasis, yet
the pathologic mechanism behind this development remains poorly understood. Here, we …

MicroRNAs (miRNA) play important roles in fine-tuning gene expression and are often
deregulated in cancer. The identification of competing endogenous RNA and circular RNA …

Both hereditary and sporadic breast cancer are suggested to develop from a stem cell
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …