Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability
Filamentous fungi drive carbon and nutrient cycling across our global ecosystems, through
its interactions with growing and decaying flora and their constituent microbiomes. The …
its interactions with growing and decaying flora and their constituent microbiomes. The …
Filamentous fungi for the production of enzymes, chemicals and materials
HAB Wösten - Current opinion in biotechnology, 2019 - Elsevier
Highlights•Fungi can be used as a cell factory and for production of mycelium
materials.•Monofungal and mixed fungal cultures produce different profiles of secreted …
materials.•Monofungal and mixed fungal cultures produce different profiles of secreted …
A Transcriptome Meta-Analysis Proposes Novel Biological Roles for the Antifungal Protein AnAFP in Aspergillus niger
N Paege, S Jung, P Schäpe, D Müller-Hagen… - PLoS …, 2016 - journals.plos.org
Understanding the genetic, molecular and evolutionary basis of cysteine-stabilized
antifungal proteins (AFPs) from fungi is important for understanding whether their function is …
antifungal proteins (AFPs) from fungi is important for understanding whether their function is …
The FlbA-regulated predicted transcription factor Fum21 of Aspergillus niger is involved in fumonisin production
D Aerts, EE Hauer, RA Ohm, M Arentshorst… - Antonie Van …, 2018 - Springer
Aspergillus niger secretes proteins throughout the colony except for the zone that forms
asexual spores called conidia. Inactivation of flbA that encodes a regulator of G-protein …
asexual spores called conidia. Inactivation of flbA that encodes a regulator of G-protein …
[HTML][HTML] Functional analysis of FlbA-regulated transcription factor genes in Aspergillus niger using a multiplexed CRISPRoff system
X Chen, JPM Torres, SVK Tedjai, LG Lugones… - International Journal of …, 2024 - Elsevier
FlbA of Aspergillus niger (indirectly) regulates 36 transcription factor (TF) genes. As a result,
it promotes sporulation and represses vegetative growth, protein secretion and lysis. In this …
it promotes sporulation and represses vegetative growth, protein secretion and lysis. In this …
[HTML][HTML] The pleiotropic phenotype of FlbA of Aspergillus niger is explained in part by the activity of seven of its downstream-regulated transcription factors
X Chen, JPM Torres, PJ Vonk, JMA Damen… - Fungal Genetics and …, 2024 - Elsevier
Inactivation of flbA in Aspergillus niger results in thinner cell walls, increased cell lysis,
abolished sporulation, and an increased secretome complexity. A total of 36 transcription …
abolished sporulation, and an increased secretome complexity. A total of 36 transcription …
FluG affects secretion in colonies of Aspergillus niger
Colonies of Aspergillus niger are characterized by zonal heterogeneity in growth,
sporulation, gene expression and secretion. For instance, the glucoamylase gene glaA is …
sporulation, gene expression and secretion. For instance, the glucoamylase gene glaA is …
FlbA-Regulated Gene rpnR Is Involved in Stress Resistance and Impacts Protein Secretion when Aspergillus niger Is Grown on Xylose
D Aerts, SG van den Bergh, H Post… - Applied and …, 2019 - Am Soc Microbiol
Proteins are secreted throughout the mycelium of Aspergillus niger except for the
sporulating zone. A link between sporulation and repression of protein secretion was …
sporulating zone. A link between sporulation and repression of protein secretion was …
Involvement of a G Protein Regulatory Circuit in Alternative Oxidase Production in Neurospora crassa
N Bosnjak, KM Smith, I Asaria… - G3: Genes …, 2019 - academic.oup.com
The Neurospora crassa nuclear aod-1 gene encodes an alternative oxidase that functions in
mitochondria. The enzyme provides a branch from the standard electron transport chain by …
mitochondria. The enzyme provides a branch from the standard electron transport chain by …
Effects of different carbon sources on the oxidative stress tolerance of Aspergillus niger HY2 isolated from spoiled paddies
S Tan, Y Xu, H Wu, A Niu, X Yin… - FEMS Microbiology …, 2022 - academic.oup.com
Fungi often experience oxidative stress in response to the environment during growth. In this
study, Aspergillus niger HY2, whose presence easily results in paddy mildew, was used to …
study, Aspergillus niger HY2, whose presence easily results in paddy mildew, was used to …