An overview of biological macromolecule crystallization
The elucidation of the three dimensional structure of biological macromolecules has
provided an important contribution to our current understanding of many basic mechanisms …
provided an important contribution to our current understanding of many basic mechanisms …
The non-classical nucleation of crystals: microscopic mechanisms and applications to molecular crystals, ice and calcium carbonate
RP Sear - International Materials Reviews, 2012 - Taylor & Francis
Crystals form via nucleation followed by growth. Often nucleation data are interpreted using
the classical theory of nucleation, which is essentially a simple theory for the nucleation of a …
the classical theory of nucleation, which is essentially a simple theory for the nucleation of a …
Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain
Methylation of the N6 position of selected internal adenines (m6A) in mRNAs and noncoding
RNAs is widespread in eukaryotes, and the YTH domain in a collection of proteins …
RNAs is widespread in eukaryotes, and the YTH domain in a collection of proteins …
Surface-induced crystallization of pharmaceuticals and biopharmaceuticals: A review
Despite the wide occurrence of crystallization in the pharmaceutical industry, deep
understanding and fine control of the process remain a tricky issue. Nevertheless, the …
understanding and fine control of the process remain a tricky issue. Nevertheless, the …
Porous nucleating agents for protein crystallization
S Khurshid, E Saridakis, L Govada, NE Chayen - Nature protocols, 2014 - nature.com
Solving the structure of proteins is pivotal to achieving success in rational drug design and in
other biotechnological endeavors. The most powerful method for determining the structure of …
other biotechnological endeavors. The most powerful method for determining the structure of …
Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence
Macromolecular crystallography suffers from two major issues: getting well-diffracting
crystals and solving the phase problem inherent to large macromolecules. Here, we …
crystals and solving the phase problem inherent to large macromolecules. Here, we …
Towards a 'universal'nucleant for protein crystallization
E Saridakis, NE Chayen - Trends in biotechnology, 2009 - cell.com
The expression 'crystal clear'stems from the science of crystallography, which determines
the detailed atomic structures of materials by exposing crystals to X-rays. Protein structures …
the detailed atomic structures of materials by exposing crystals to X-rays. Protein structures …
Random microseeding: a theoretical and practical exploration of seed stability and seeding techniques for successful protein crystallization
Microseed matrix-screening combined with random screens (rMMS) is a significant recent
breakthrough in protein crystallization. In this study, a very reproducible assay for crystal …
breakthrough in protein crystallization. In this study, a very reproducible assay for crystal …
Advancements (and challenges) in the study of protein crystal nucleation and growth; thermodynamic and kinetic explanations and comparison with small-molecule …
CN Nanev - Progress in Crystal Growth and Characterization of …, 2020 - Elsevier
This paper reviews advancements and some novel ideas (not yet covered by reviews and
monographs) concerning thermodynamics and kinetics of protein crystal nucleation and …
monographs) concerning thermodynamics and kinetics of protein crystal nucleation and …
Protein crystal nucleation in pores
The most powerful method for protein structure determination is X-ray crystallography which
relies on the availability of high quality crystals. Obtaining protein crystals is a major …
relies on the availability of high quality crystals. Obtaining protein crystals is a major …