The discovery of the carcinoembryonic antigen (CEA) as a tumor marker for colorectal
cancer some 50 years ago became the first step in the identification of a much larger family …

Pancreatic cancer (PC) is a leading cause of cancer related mortality on a global scale. The
disease itself is associated with a dismal prognosis, partly due to its silent nature resulting in …

Targeting the dynamic tumor immune microenvironment (TIME) can provide effective
therapeutic strategies for cancer. Neutrophils are the predominant leukocyte population in …

Background Immunotherapy has revolutionized clinical outcomes for patients suffering from
lung cancer, yet relatively few patients sustain long-term durable responses. Recent studies …

The liver is host to many metastatic cancers, particularly colorectal cancer, for which the last
2 decades have seen major advances in diagnosis and treatment. The liver is a vital organ …

Fusobacterium nucleatum (F. nucleatum) is an oral anaerobe found to be enriched in
colorectal cancer (CRC). Presence of F. nucleatum in CRC has been correlated with …

ABSTRACT CEACAM1 is an extensively studied cell surface molecule with established
functions in multiple cancer types, as well as in various compartments of the immune system …

Neutrophils promote tumor growth and metastasis at multiple stages of cancer progression.
One mechanism through which this occurs is via release of neutrophil extracellular traps …

Intercellular adhesion molecule (ICAM)-1, is a transmembrane glycoprotein of the
immunoglobulin (Ig)-like superfamily, consisting of five extracellular Ig-like domains, a …

Background Aim of this study was to assess the biological function in tumor progression and
metastatic process carcinoembryonic antigen-related cell adhesion molecules (CEACAM) 1 …