Important flavonoids and their role as a therapeutic agent

A Ullah, S Munir, SL Badshah, N Khan, L Ghani… - Molecules, 2020‏ - mdpi.com
Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and
leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of …

[HTML][HTML] Umbelliferone and its synthetic derivatives as suitable molecules for the development of agents with biological activities: a review of their pharmacological and …

A Kornicka, Ł Balewski, M Lahutta, J Kokoszka - Pharmaceuticals, 2023‏ - mdpi.com
Umbelliferone (UMB), known as 7-hydroxycoumarin, hydrangine, or skimmetine, is a
naturally occurring coumarin in the plant kingdom, mainly from the Umbelliferae family that …

Solvent polarity mediates phytochemical yield and antioxidant capacity of Isatis tinctoria

A Wakeel, SA Jan, I Ullah, ZK Shinwari, M Xu - PeerJ, 2019‏ - peerj.com
Secondary metabolites have been extensively used in the treatment of various health
problems. The role of solvent polarity on the phytochemical isolation and antioxidant …

[HTML][HTML] Non-alkaloid cholinesterase inhibitory compounds from natural sources

AN Tamfu, S Kucukaydin, B Yeskaliyeva, M Ozturk… - Molecules, 2021‏ - mdpi.com
Alzheimer's disease (AD) is a severe neurodegenerative disorder of different brain regions
accompanied by distresses and affecting more than 25 million people in the world. This …

Umbelliferon: a review of its pharmacology, toxicity and pharmacokinetics

Z Lin, X Cheng, H Zheng - Inflammopharmacology, 2023‏ - Springer
Coumarin, a plant secondary metabolite, has various pharmacological activities, including
antioxidant stress and anti-inflammatory effects. Umbelliferone, a common coumarin …

[HTML][HTML] Neuroprotective, neurite enhancing, and cholinesterase inhibitory effects of Lamiaceae family essential oils in Alzheimer's disease model

WN Chen, KW Chin, K San Tang… - Journal of Herbal …, 2023‏ - Elsevier
Introduction The present study investigates the cholinesterase inhibitory and neuritogenic
activities of selected essential oils from the Lamiaceae family, as well as their …

Antioxidant, Antifungal and Phytochemical Investigations of Capparis spinosa L.

I Rajhi, F Hernandez-Ramos, M Abderrabba… - Agriculture, 2021‏ - mdpi.com
The antioxidant and antifungal activities of crude hydro-ethanolic extract from Capparis
spinosa L.(Capparidaceae) leaves and their fractions, obtained by liquid-liquid extraction …

Cholinesterase inhibitory potential of quercetin towards Alzheimer's disease-a promising natural molecule or fashion of the day?-A narrowed review

IE Orhan - Current Neuropharmacology, 2021‏ - benthamdirect.com
Natural substances are known to have strong protective effects against neurodegenerative
diseases. Among them, phenolic compounds, especially flavonoids, come to the fore with …

Furanocoumarins: history of research, diversity, synthesis, physiological role in the plant, and medical application

VY Shtratnikova - Russian Journal of Plant Physiology, 2023‏ - Springer
The review is devoted to furanocoumarins, a class of substances that are a combination of
pyrone, benzene, and furan rings, possessing a system of conjugated double bonds (which …

[HTML][HTML] Phenolic Composition and Biological Properties of Cynara cardunculus L. var. altilis Petioles: Influence of the Maturity Stage

F Mandim, SA Petropoulos, MI Dias, J Pinela, M Kostić… - Antioxidants, 2021‏ - mdpi.com
Hydroethanolic extracts of cardoon petioles collected at sixteen growth stages (P1–P16)
were characterized in terms of their phenolic composition and bioactive potential …