VEGF/VEGFR-targeted therapy and immunotherapy in non-small cell lung cancer: targeting the tumor microenvironment
Non-small cell lung cancer (NSCLC) is the leading cause of death by cancer worldwide.
Despite developments in therapeutic approaches for the past few decades, the 5-year …
Despite developments in therapeutic approaches for the past few decades, the 5-year …
[HTML][HTML] The bidirectional immune crosstalk in metabolic dysfunction-associated steatotic liver disease
K Sawada, H Chung, S Softic, ME Moreno-Fernandez… - Cell metabolism, 2023 - cell.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) is an unabated risk factor
for end-stage liver diseases with no available therapies. Dysregulated immune responses …
for end-stage liver diseases with no available therapies. Dysregulated immune responses …
The role of PD-1 signaling in health and immune-related diseases
RY Chen, Y Zhu, YY Shen, QY Xu, HY Tang… - Frontiers in …, 2023 - frontiersin.org
Programmed cell death 1 receptor (PD-1) and its ligands constitute an inhibitory pathway to
mediate the mechanism of immune tolerance and provide immune homeostasis …
mediate the mechanism of immune tolerance and provide immune homeostasis …
New insights into checkpoint inhibitor immunotherapy and its combined therapies in hepatocellular carcinoma: from mechanisms to clinical trials
H **, S Qin, J He, J ** microvascular capillaries, where they
support vasculature functioning, participate in tissue regeneration, and regulate blood flow …
support vasculature functioning, participate in tissue regeneration, and regulate blood flow …
Reversing T-cell exhaustion in immunotherapy: a review on current approaches and limitations
Introduction: T cell functions are altered during chronic viral infections and tumor
development. This is mainly manifested by significant changes in T cells' epigenetic and …
development. This is mainly manifested by significant changes in T cells' epigenetic and …
[HTML][HTML] Phage display-based nanotechnology applications in cancer immunotherapy
M Goracci, Y Pignochino, S Marchiò - Molecules, 2020 - mdpi.com
Phage display is a nanotechnology with limitless potential, first developed in 1985 and still
awaiting to reach its peak. Awarded in 2018 with the Nobel Prize for Chemistry, the method …
awaiting to reach its peak. Awarded in 2018 with the Nobel Prize for Chemistry, the method …
A Prognostic Microenvironment-Related Immune Signature via ESTIMATE (PROMISE Model) Predicts Overall Survival of Patients With Glioma
H Qiu, Y Li, S Cheng, J Li, C He, J Li - Frontiers in oncology, 2020 - frontiersin.org
Objective In the development of immunotherapies in gliomas, the tumor microenvironment
(TME) needs to be investigated. We aimed to construct a prognostic microenvironment …
(TME) needs to be investigated. We aimed to construct a prognostic microenvironment …
EGC enhances tumor antigen presentation and CD8+ T cell-mediated antitumor immunity via targeting oncoprotein SND1
X Zhang, X Cui, P Li, Y Zhao, Y Ren, H Zhang, S Zhang… - Cancer Letters, 2024 - Elsevier
Abstract The Staphylococcal nuclease and Tudor domain containing 1 (SND1) has been
identified as an oncoprotein. Our previous study demonstrated that SND1 impedes the major …
identified as an oncoprotein. Our previous study demonstrated that SND1 impedes the major …