As one of the most prevalent neurotrophic factors in the central nervous system (CNS), brain-
derived neurotrophic factor (BDNF) plays a significant role in CNS injury by binding to its …

Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG expansion in
the HD gene. The disease is characterized by neurodegeneration, particularly in the striatum …

Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor
(NGF) and brain-derived neurotrophic factor (BDNF) are important for the survival …

Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat
expansion in the gene encoding for huntingtin protein. A lot has been learned about this …

Neurotrophic factors are essential contributors to the survival of peripheral and central
nervous system (CNS) neurons, and demonstration of their reduced availability in diseased …

Our knowledge of the pathophysiology about traumatic brain injury (TBI) is still limited.
Neutrophils, as the most abundant leukocytes in circulation and the first-line transmigrated …

The growth factor brain-derived neurotrophic factor (BDNF), and its receptor tropomyosin-
related kinase receptor type B (TrkB) play an active role in numerous areas of the adult …

Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, modulates
neuronal survival, differentiation, and synaptic function. Reduced BDNF expression in the …

In addition to neurological deficits, Huntington's disease (HD) patients and transgenic mice
expressing mutant human huntingtin exhibit reduced levels of brain-derived neurotrophic …

Huntington's disease (HD) is a fatal degenerative autosomal dominant neuropsychiatric
disease that causes neuronal death and is characterized by progressive striatal and then …