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[HTML][HTML] Lipid-core nanoparticles: Classification, preparation methods, routes of administration and recent advances in cancer treatment
Nanotechnological drug delivery platforms represent a new paradigm for cancer
therapeutics as they improve the pharmacokinetic profile and distribution of …
therapeutics as they improve the pharmacokinetic profile and distribution of …
A review on polymer and lipid-based nanocarriers and its application to nano-pharmaceutical and food-based systems
H Lu, S Zhang, J Wang, Q Chen - Frontiers in nutrition, 2021 - frontiersin.org
Recently, owing to well-controlled release, enhanced distribution and increased
permeability, nanocarriers used for alternative drug and food-delivery strategies have …
permeability, nanocarriers used for alternative drug and food-delivery strategies have …
Nanoprecipitation process: From encapsulation to drug delivery
Drugs encapsulation is a suitable strategy in order to cope with the limitations of
conventional dosage forms such as unsuitable bioavailability, stability, taste, and odor …
conventional dosage forms such as unsuitable bioavailability, stability, taste, and odor …
[HTML][HTML] Tailoring formulations for intranasal nose-to-brain delivery: a review on architecture, physico-chemical characteristics and mucociliary clearance of the nasal …
The blood-brain barrier and the blood-cerebrospinal fluid barrier are major obstacles in
central nervous system (CNS) drug delivery, since they block most molecules from entering …
central nervous system (CNS) drug delivery, since they block most molecules from entering …
Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come
P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - Elsevier
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …
Doxorubicin: nanotechnological overviews from bench to bedside
M Cagel, E Grotz, E Bernabeu, MA Moretton… - Drug discovery today, 2017 - Elsevier
Highlights•Doxorubicin (DOX) is considered one of the most effective chemotherapeutic
agents.•Dose-cumulative cardiotoxicity is the most dangerous adverse effect.•DOX-based …
agents.•Dose-cumulative cardiotoxicity is the most dangerous adverse effect.•DOX-based …
From adsorption to covalent bonding: Apolipoprotein E functionalization of polymeric nanoparticles for drug delivery across the blood–brain barrier
The blood–brain barrier (BBB) is composed of brain endothelial cells, pericytes, and
astrocytes, which build a tight cellular barrier. Therapeutic (macro) molecules are not able to …
astrocytes, which build a tight cellular barrier. Therapeutic (macro) molecules are not able to …
Absorption, distribution, metabolism and excretion of the biomaterials used in Nanocarrier drug delivery systems
Nanocarriers (NCs) are a type of drug delivery system commonly used to regulate the
pharmacokinetic and pharmacodynamic properties of drugs. Although a wide variety of NCs …
pharmacokinetic and pharmacodynamic properties of drugs. Although a wide variety of NCs …
Polymer nanoparticles for the intravenous delivery of anticancer drugs: the checkpoints on the road from the synthesis to clinical translation
In this review article we discuss some of the key aspects concerning the development of a
polymer-based nanoparticle formulation for intravenous drug delivery. Since numerous …
polymer-based nanoparticle formulation for intravenous drug delivery. Since numerous …
Drug delivery vehicles on a nano-engineering perspective
Nanoengineered drug delivery systems (nDDS) have been successfully used as clinical
tools for not only modulation of pharmacological drug release profile but also specific …
tools for not only modulation of pharmacological drug release profile but also specific …