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[HTML][HTML] Current understanding of asthma pathogenesis and biomarkers
N Habib, MA Pasha, DD Tang - Cells, 2022 - mdpi.com
Asthma is a heterogeneous lung disease with variable phenotypes (clinical presentations)
and distinctive endotypes (mechanisms). Over the last decade, considerable efforts have …
and distinctive endotypes (mechanisms). Over the last decade, considerable efforts have …
Advances and recent developments in asthma in 2020
In this review, we discuss recent publications on asthma and review the studies that have
reported on the different aspects of the prevalence, risk factors and prevention, mechanisms …
reported on the different aspects of the prevalence, risk factors and prevention, mechanisms …
Omics technologies in allergy and asthma research: an EAACI position paper
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …
several distinct complex endotypes. Both environmental and genetic factors can influence …
[HTML][HTML] Severe asthma and biological therapies: now and the future
O Sardon-Prado, C Diaz-Garcia… - Journal of Clinical …, 2023 - mdpi.com
Recognition of phenotypic variability in pediatric asthma allows for a more personalized
therapeutic approach. Knowledge of the underlying pathophysiological and molecular …
therapeutic approach. Knowledge of the underlying pathophysiological and molecular …
Gasdermin B, an asthma-susceptibility gene, promotes MAVS-TBK1 signalling and airway inflammation
Rationale Respiratory virus-induced inflammation is the leading cause of asthma
exacerbation, frequently accompanied by induction of interferon-stimulated genes (ISGs) …
exacerbation, frequently accompanied by induction of interferon-stimulated genes (ISGs) …
The effects of the environment on asthma disease activity
M Louisias, A Ramadan, AS Naja… - … and allergy clinics of …, 2019 - pmc.ncbi.nlm.nih.gov
Asthma is one of the most common chronic conditions in children with the highest
prevalence rates among Puerto Ricans and Blacks and minority communities1, 2. It is …
prevalence rates among Puerto Ricans and Blacks and minority communities1, 2. It is …
Omics for the future in asthma
MI Abdel-Aziz, AH Neerincx, SJ Vijverberg… - Seminars in …, 2020 - Springer
Asthma is a common, complex, multifaceted disease. It comprises multiple phenotypes,
which might benefit from treatment with different types of innovative targeted therapies …
which might benefit from treatment with different types of innovative targeted therapies …
The Pathogenesis of Eosinophilic Asthma: A Positive Feedback Mechanism That Promotes Th2 Immune Response via Filaggrin Deficiency
W Gao, J Gong, M Mu, Y Zhu, W Wang… - Frontiers in …, 2021 - frontiersin.org
Eosinophilic asthma (EA) is a common subtype of asthma and often progresses to severe
disease. In order to understand its pathogenesis, targeted next-generation gene sequencing …
disease. In order to understand its pathogenesis, targeted next-generation gene sequencing …
Genetic associations of the response to inhaled corticosteroids in asthma: a systematic review
There is wide variability in the response to inhaled corticosteroids (ICS) in asthma. While
some of this heterogeneity of response is due to adherence and environmental causes …
some of this heterogeneity of response is due to adherence and environmental causes …
Immune responsiveness to LPS determines risk of childhood wheeze and asthma in 17q21 risk allele carriers
S Illi, M Depner, PI Pfefferle, H Renz… - American journal of …, 2022 - atsjournals.org
Rationale: In murine models, microbial exposures induce protection from experimental
allergic asthma through innate immunity. Objectives: Our aim was to assess the association …
allergic asthma through innate immunity. Objectives: Our aim was to assess the association …