Converting nanotoxicity data to information using artificial intelligence and simulation

X Yan, T Yue, DA Winkler, Y Yin, H Zhu… - Chemical …, 2023‏ - ACS Publications
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …

Nanoenabled intracellular metal ion homeostasis regulation for tumor therapy

L Xu, M Peng, T Gao, D Wang, X Lian, H Sun… - Advanced …, 2024‏ - Wiley Online Library
Endogenous essential metal ions play an important role in many life processes, especially in
tumor development and immune response. The approval of various metallodrugs for tumor …

Form follows function: nanoparticle shape and its implications for nanomedicine

C Kinnear, TL Moore, L Rodriguez-Lorenzo… - Chemical …, 2017‏ - ACS Publications
This review is a comprehensive description of the past decade of research into
understanding how the geometry and size of nanoparticles affect their interaction with …

Size and charge effects of metal nanoclusters on antibacterial mechanisms

HT Draviana, I Fitriannisa, M Khafid… - Journal of …, 2023‏ - Springer
Nanomaterials, specifically metal nanoclusters (NCs), are gaining attention as a promising
class of antibacterial agents. Metal NCs exhibit antibacterial properties due to their …

Recent development of gold nanoparticles as contrast agents for cancer diagnosis

D Luo, X Wang, C Burda, JP Basilion - Cancers, 2021‏ - mdpi.com
Simple Summary The development of nanotechnology has brought revolution to the
diagnosis and therapy of diseases, with a high precision and efficacy. Because …

Simulation of nanoparticles interacting with a cell membrane: probing the structural basis and potential biomedical application

X Zhang, G Ma, W Wei - NPG Asia Materials, 2021‏ - nature.com
Nanoparticles (NPs), owing to their ultrasmall size, have been extensively researched for
potential applications in biomedicine. During their delivery and functionalization within the …

Understanding nanoparticle cellular entry: a physicochemical perspective

CM Beddoes, CP Case, WH Briscoe - Advances in colloid and interface …, 2015‏ - Elsevier
Understanding interactions between nanoparticles (NPs) with biological matter, particularly
cells, is becoming increasingly important due to their growing application in medicine and …

Theoretical and computational investigations of nanoparticle–biomembrane interactions in cellular delivery

H Ding, Y Ma - Small, 2015‏ - Wiley Online Library
With the rapid development of nanotechnology, nanoparticles have been widely used in
many applications such as phototherapy, cell imaging, and drug/gene delivery. A better …

Shape effect in cellular uptake of PEGylated nanoparticles: comparison between sphere, rod, cube and disk

Y Li, M Kröger, WK Liu - Nanoscale, 2015‏ - pubs.rsc.org
The size, shape, surface property and material composition of polymer-coated nanoparticles
(NPs) are four important parameters in designing efficient NP-based carriers for targeted …

Target delivery and cell imaging using hyaluronic acid-functionalized graphene quantum dots

JE Lee, I In, H Lee, KD Lee, JH Jeong… - Molecular …, 2013‏ - ACS Publications
This work demonstrates the way to achieve efficient and target specific delivery of a
graphene quantum dot (GQD) using hyaluronic acid (HA)(GQD-HA) as a targeting agent. HA …