[HTML][HTML] A comprehensive review on pharmacological applications and drug-induced toxicity of valproic acid
Valproic acid, a branching short chain fatty acid, is a popular drug to treat epilepsy and acts
as a mood-stabilizing drug. The obstruction of ion channels and Gamma Amino Butyrate …
as a mood-stabilizing drug. The obstruction of ion channels and Gamma Amino Butyrate …
How I evaluate and treat thrombocytopenia in the intensive care unit patient
A Greinacher, S Selleng - Blood, The Journal of the American …, 2016 - ashpublications.org
Multiple causes (pseudothrombocytopenia, hemodilution, increased consumption,
decreased production, increased sequestration, and immune-mediated destruction of …
decreased production, increased sequestration, and immune-mediated destruction of …
The International Society for Bipolar Disorders (ISBD) consensus guidelines for the safety monitoring of bipolar disorder treatments
F Ng, OK Mammen, I Wilting, GS Sachs… - Bipolar …, 2009 - Wiley Online Library
Objectives: Safety monitoring is an important aspect of bipolar disorder treatment, as mood‐
stabilising medications have potentially serious side effects, some of which may also …
stabilising medications have potentially serious side effects, some of which may also …
Valproate‐induced thrombocytopenia: a prospective monotherapy study
Purpose: The frequency of valproate (VPA)‐induced thrombocytopenia varied widely in
previous studies, due to methodological differences. Our objective was to evaluate the …
previous studies, due to methodological differences. Our objective was to evaluate the …
Drug-induced immune thrombocytopenia
PMLA Van den Bemt, RHB Meyboom, ACG Egberts - Drug Safety, 2004 - Springer
Thrombocytopenia can have several causes, including the use of certain drugs. The
mechanism behind drug-induced thrombocytopenia is either a decrease in platelet …
mechanism behind drug-induced thrombocytopenia is either a decrease in platelet …
A review of valproate in psychiatric practice
PM Haddad, A Das, M Ashfaq… - Expert opinion on drug …, 2009 - Taylor & Francis
Valproate (2-propylpentanoate) is available as valproic acid, sodium valproate and
semisodium valproate. It has actions on dopamine, GABA and glutamate neurotransmission …
semisodium valproate. It has actions on dopamine, GABA and glutamate neurotransmission …
Valproic acid for treatment of hyperactive or mixed delirium: rationale and literature review
Y Sher, ACM Cramer, A Ament, S Lolak, JR Maldonado - Psychosomatics, 2015 - Elsevier
Background Delirium is the most often encountered psychiatric diagnosis in the general
hospital, with an incidence of up to 82% in the intensive care unit setting and with significant …
hospital, with an incidence of up to 82% in the intensive care unit setting and with significant …
Safety range of free valproic acid serum concentration in adult patients
YJ Tseng, SY Huang, CH Kuo, CY Wang, KC Wang… - PLoS …, 2020 - journals.plos.org
Background Therapeutic drug monitoring (TDM) is recommended during valproic acid (VPA)
use, and total serum concentration has been widely adopted. However, the free form of VPA …
use, and total serum concentration has been widely adopted. However, the free form of VPA …
Alcohol withdrawal syndrome in neurocritical care unit: assessment and treatment challenges
Alcohol withdrawal syndrome (AWS) can range from mild jittery movements, nausea,
sweating to more severe symptoms such as seizure and death. Severe AWS can worsen …
sweating to more severe symptoms such as seizure and death. Severe AWS can worsen …
Valproate for agitation in critically ill patients: a retrospective study
Purpose The purpose was to describe the use of valproate therapy for agitation in critically ill
patients, examine its safety, and describe its relationship with agitation and delirium …
patients, examine its safety, and describe its relationship with agitation and delirium …