Determining the causes of schizophrenia has been a notoriously intractable problem,
resistant to a multitude of investigative approaches over centuries. In recent decades …

Schizophrenia is a debilitating psychiatric disorder that affects millions of people worldwide;
however, its etiology is poorly understood at the molecular and neurobiological levels. A …

The ever-growing compendium of genetic variants associated with human pathologies
demands new methods to study genotype–phenotype relationships in complex tissues in a …

Despite enormous efforts employing various approaches, the molecular pathology in the
schizophrenia brain remains elusive. On the other hand, the knowledge of the association …

Thalamic dysfunction has been implicated in multiple psychiatric disorders. We sought to
study the mechanisms by which abnormalities emerge in the context of the 22q11. 2 …

Genetic research in Autism Spectrum Disorder (ASD) has progressed tremendously in
recent decades. Dozens of genetic loci and hundreds of alterations in the genetic sequence …

Since more than 3 decades, schizophrenia (SZ) has been regarded as a
neurodevelopmental disorder. The neurodevelopmental hypothesis proposes that SZ is …

Rare recurrent copy number variants (CNVs) at chromosomal loci 22q11. 2 and 16p11. 2
are genetic disorders with lifespan risk for neuropsychiatric disorders. Microdeletions and …

The number of individuals suffering from neuropsychiatric disorders (NPDs) has increased
worldwide, with 3 million disability-adjusted life-years calculated in 2019. Though research …

Neurodevelopmental disorders (NDDs) are associated with a wide range of clinical features,
affecting multiple pathways involved in brain development and function. Recent advances in …