Recent advances in viral metagenomics have enabled the rapid discovery of an
unprecedented catalogue of phages in numerous environments, from the human gut to the …

Viruses and mobile genetic elements are molecular parasites or symbionts that coevolve
with nearly all forms of cellular life. The route of virus replication and protein expression is …

African swine fever virus (ASFV) is a giant and complex DNA virus that causes a highly
contagious and often lethal swine disease for which no vaccine is available. Using an …

Within the materials science community, proteins with cage-like architectures are being
developed as versatile nanoscale platforms for use in protein nanotechnology. Much effort …

Healthcare faces a major problem with the increased emergence of antimicrobial resistance
due to over-prescribing antibiotics. Bacteriophages may provide a solution to the treatment …

Adenoviruses have been studied intensively for over 50 years as models of virus–cell
interactions and latterly as gene vectors. With the advent of more sophisticated structural …

Construction of a complex virus may involve a hierarchy of assembly elements. Here, we
report the structure of the whole human adenovirus virion at 3.6 angstroms resolution by …

The endocytic network comprises a series of interconnected tubulo-vesicular membranous
compartments that together regulate various sorting and signalling events. Although it is …

Recent advances in synchrotron sources, beamline optics and detectors are driving a
renaissance in room-temperature data collection. The underlying impetus is the recognition …

Is it possible to meaningfully comprehend the diversity of the viral world? We propose that it
is. This is based on the observation that, although there is immense genomic variation, every …