With the aging of population and the rapid improvement of public health and medical level in
recent years, people have had an increasing demand for orthopedic implants. However …

The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …

Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

Diabetic wound is one of the most intractable chronic wounds that is prone to bacterial
infection. Hypoxia is an important feature in its microenvironment. However, it is challenging …

Bacterial infections, especially those caused by drug-resistant bacteria, have seriously
threatened human life and health. There is urgent to develop new antibacterial agents to …

Misuse and overuse of antibiotics led us vulnerable to multi-drug resistant (MDR) bacteria,
biofilms, and intracellular infections. The failure of conventional antibiotics thus gives rise to …

Antibacterial coatings that eliminate initial bacterial attachment and prevent subsequent
biofilm formation are essential in a number of applications, especially implanted medical …

Microbial resistance has increased in recent decades as a result of the extensive and
indiscriminate use of antibiotics. The World Health Organization listed antimicrobial …

Skin is the first line of defense against pathogenic microorganisms. Any serious damage to
this organ can lead to bacterial invasion and wound infection. Such infections can cause not …