Arteries exhibit a remarkable ability to adapt to diverse genetic defects and sustained
alterations in mechanical loading. For example, changes in blood flow induced wall shear …

The primary function of central arteries is to store elastic energy during systole and to use it
to sustain blood flow during diastole. Arterial stiffening compromises this normal mechanical …

Arterial tortuosity manifests in many conditions, including hypertension, genetic mutations
predisposing to thoracic aortopathy, and vascular aging. Despite evidence that tortuosity …

Objective—Williams syndrome is characterized by obstructive aortopathy attributable to
heterozygous loss of ELN, the gene encoding elastin. Lesions are thought to result primarily …

Objective: The aim of the study was to investigate whether functional changes and structural
remodeling occurs in the microvascular bed of the pulmonary circulation under nonpulsatile …

Opening angles (OAs) are associated with growth and remodelling in arteries. One curiosity
has been the relatively large OAs found in the aortic arch of some animals. Here, we use …

Studies were performed to examine the extent to which mechanical stimuli mediate control
of angiogenesis in bladder cells both in vitro and in vivo. Differential gene expression …

The prevalence of hypertension increases with aging and is associated with increased
arterial stiffness. Resistant hypertension is presented when drug treatments fail to regulate a …

Vascular endothelial cells display a wide panel of responses to changes in the shear stress
that is exerted on them by blood flow. How sensory mechanisms convey information about …

The purpose of this manuscript is to establish a unified theory of porohyperelasticity with
transport and growth and to demonstrate the capability of this theory using a finite element …