Chimeric antigen receptors (CARs) are widely used by T cells (CAR-T cells), natural killer
cells dendritic cells and macrophages, and they are of great importance in cellular …

Human corneal transplantation (keratoplasty) is typically considered to have superior short-
and long-term outcomes and lower requirement for immunosuppression compared to solid …

Osteoarthritis (OA) has become recognized as a low-grade inflammatory state. Inflammatory
infiltration of the synovium by macrophages, T cells, B cells, and other immune cells is often …

Congenital aniridia is a panocular disorder that is typically characterized by iris hypoplasia
and aniridia-associated keratopathy (AAK). AAK results in the progressive loss of corneal …

The global shortage of donor corneas for transplantation has led to corneal bioengineering
being investigated as a method to generate transplantable tissues. Decellularized corneas …

Mesenchymal stromal cells (MSCs) are a promising therapeutic option for multiple immune
diseases/disorders; however, efficacy of MSC treatments can vary significantly. We present a …

Mesenchymal stromal cells (MSCs) have shown promise as a therapy for immune‐mediated
disorders, including transplant rejection. Our group previously demonstrated the efficacy of …

High-risk cornea transplant recipients represent a patient population with significant un-met
medical need for more effective therapies to prevent immunological graft rejection due to …

Affecting a large proportion of the population worldwide, corneal disorders constitute a
concerning health hazard associated to compromised eyesight or blindness for most severe …

Abstract Background Fungal Keratitis (FK) is an infective keratopathy with extremely high
blindness rate. The damaging effect of this disease is not only the destruction of corneal …