Assessment of Ki67 in breast cancer: updated recommendations from the international Ki67 in breast cancer working group

TO Nielsen, SCY Leung, DL Rimm… - JNCI: Journal of the …, 2021 - academic.oup.com
Abstract Ki67 immunohistochemistry (IHC), commonly used as a proliferation marker in
breast cancer, has limited value for treatment decisions due to questionable analytical …

Overview of multiplex immunohistochemistry/immunofluorescence techniques in the era of cancer immunotherapy

WCC Tan, SN Nerurkar, HY Cai, HHM Ng… - Cancer …, 2020 - Wiley Online Library
Conventional immunohistochemistry (IHC) is a widely used diagnostic technique in tissue
pathology. However, this technique is associated with a number of limitations, including high …

[HTML][HTML] Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study

N Harbeck, P Rastogi, M Martin, SM Tolaney… - Annals of …, 2021 - Elsevier
Background Adjuvant abemaciclib combined with endocrine therapy (ET) previously
demonstrated clinically meaningful improvement in invasive disease-free survival (IDFS) …

Artificial intelligence in breast cancer diagnosis and personalized medicine

JS Ahn, S Shin, SA Yang, EK Park… - Journal of Breast …, 2023 - pmc.ncbi.nlm.nih.gov
Breast cancer is a significant cause of cancer-related mortality in women worldwide. Early
and precise diagnosis is crucial, and clinical outcomes can be markedly enhanced. The rise …

Artificial intelligence as the next step towards precision pathology

B Acs, M Rantalainen, J Hartman - Journal of internal medicine, 2020 - Wiley Online Library
Pathology is the cornerstone of cancer care. The need for accuracy in histopathologic
diagnosis of cancer is increasing as personalized cancer therapy requires accurate …

[HTML][HTML] QuPath: Open source software for digital pathology image analysis

P Bankhead, MB Loughrey, JA Fernández… - Scientific reports, 2017 - nature.com
QuPath is new bioimage analysis software designed to meet the growing need for a user-
friendly, extensible, open-source solution for digital pathology and whole slide image …

[HTML][HTML] De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of …

G Curigliano, HJ Burstein, EP Winer, M Gnant… - Annals of …, 2017 - Elsevier
ABSTRACT The 15th St. Gallen International Breast Cancer Conference 2017 in Vienna,
Austria reviewed substantial new evidence on loco-regional and systemic therapies for early …

[HTML][HTML] Tailoring therapies—improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast …

AS Coates, EP Winer, A Goldhirsch, RD Gelber… - Annals of oncology, 2015 - Elsevier
ABSTRACT The 14th St Gallen International Breast Cancer Conference (2015) reviewed
substantial new evidence on locoregional and systemic therapies for early breast cancer …

Use of biomarkers to guide decisions on adjuvant systemic therapy for women with early-stage invasive breast cancer: American Society of Clinical Oncology Clinical …

LN Harris, N Ismaila, LM McShane, F Andre… - Journal of Clinical …, 2016 - ascopubs.org
Purpose To provide recommendations on appropriate use of breast tumor biomarker assay
results to guide decisions on adjuvant systemic therapy for women with early-stage invasive …

Clinical relevance of host immunity in breast cancer: from TILs to the clinic

P Savas, R Salgado, C Denkert, C Sotiriou… - Nature reviews Clinical …, 2016 - nature.com
The clinical relevance of the host immune system in breast cancer has long been
unexplored. Studies developed over the past decade have highlighted the biological …