Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …

The ventromedial prefrontal cortex (vmPFC) has been implicated in a variety of social,
cognitive, and affective functions that are commonly disrupted in mental illness. In this …

Placebo effects are notable demonstrations of mind–body interactions,. During pain
perception, in the absence of any treatment, an expectation of pain relief can reduce the …

Placebo effects are beneficial effects that are attributable to the brain–mind responses to the
context in which a treatment is delivered rather than to the specific actions of the drug. They …

The sensory, associative and limbic neocortical structures play a critical role in sha**
incoming noxious inputs to generate variable pain perceptions. Technological advances in …

Placebo effects constitute a major part of treatment success in medical interventions. The
nocebo effect also has a major impact, as it accounts for a significant proportion of the …

The brain systems underlying placebo analgesia are insufficiently understood. Here we
performed a systematic, participant-level meta-analysis of experimental functional …

Mindfulness meditation reduces pain in experimental and clinical settings. However, it
remains unknown whether mindfulness meditation engages pain-relieving mechanisms …

Pain is a multidimensional experience that involves interacting sensory, cognitive, and
affective factors, rendering the treatment of chronic pain challenging and financially …

Non-invasive functional brain imaging is used more than ever to investigate pain in health
and disease, with the prospect of finding new means to alleviate pain and improve patient …