The genetic and environmental factors for keratoconus

A Gordon-Shaag, M Millodot… - BioMed research …, 2015 - Wiley Online Library
Keratoconus (KC) is the most common cornea ectatic disorder. It is characterized by a cone‐
shaped thin cornea leading to myopia, irregular astigmatism, and vision impairment. It …

The keratoconus enigma: a review with emphasis on pathogenesis

G Ferrari, P Rama - The ocular surface, 2020 - Elsevier
Purpose To review the literature on the etiopathogenesis of keratoconus (KC). Methods A
literature search was conducted using PUBMED and Google Scholar for keratoconus. The …

[HTML][HTML] Updates on managements for keratoconus

M Mohammadpour, Z Heidari, H Hashemi - Journal of current …, 2018 - Elsevier
Purpose Keratoconus is a progressive disease of the cornea which can lead to blindness as
irregular astigmatism increases. Currently, a variety of methods are available for the …

Genetics vs chronic corneal mechanical trauma in the etiology of keratoconus

YS Rabinowitz, V Galvis, A Tello, D Rueda… - Experimental eye …, 2021 - Elsevier
Both genetic and environmental factors have been considered to play a role in the etiology
keratoconus. Eye rubbing, and more recently eye compression due to slee** position …

Pathogenesis of Keratoconus: The intriguing therapeutic potential of Prolactin-inducible protein

R Sharif, S Bak-Nielsen, J Hjortdal… - Progress in retinal and …, 2018 - Elsevier
Keratoconus (KC) is the most common ectatic corneal disease, with clinical findings that
include discomfort, visual disturbance and possible blindness if left untreated. KC affects …

Contemporary treatment paradigms in keratoconus

CNJ McGhee, BZ Kim, PJ Wilson - Cornea, 2015 - journals.lww.com
The past 20 years have witnessed an explosion in our knowledge of keratoconus,
accompanied by a radical transformation of management options. A 2-hit hypothesis …

Genetics in Keratoconus: where are we?

Y Bykhovskaya, B Margines, YS Rabinowitz - Eye and Vision, 2016 - Springer
Keratoconus (KC) is a non-inflammatory thinning and protrusion of the cornea in which the
cornea assumes a conical shape. Complex etiology of this condition at present remains an …

Genetic and environmental risk factors for keratoconus

SEM Lucas, KP Burdon - Annual Review of Vision Science, 2020 - annualreviews.org
Keratoconus, a progressive corneal ectasia, is a complex disease with both genetic and
environmental risk factors. The exact etiology is not known and is likely variable between …

Genetic aspects of keratoconus: a literature review exploring potential genetic contributions and possible genetic relationships with comorbidities

E Loukovitis, K Sfakianakis, P Syrmakesi… - Ophthalmology and …, 2018 - Springer
Introduction Keratoconus (KC) is a complex, genetically heterogeneous, multifactorial
degenerative disorder that is accompanied by corneal ectasia which usually progresses …

The enigma of environmental factors in keratoconus

AZ Crawford, J Zhang, A Gokul… - The Asia-Pacific …, 2020 - journals.lww.com
Keratoconus is an ectatic disorder with highly complex and varied causes including genetic
variations and environmental factors. Its prevalence varies widely between regions and …