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Agarose-based biomaterials for tissue engineering
Agarose is a natural polysaccharide polymer having unique characteristics that give reason
to consider it for tissue engineering applications. Special characteristics of agarose such as …
to consider it for tissue engineering applications. Special characteristics of agarose such as …
How can machine learning and multiscale modeling benefit ocular drug development?
The eyes possess sophisticated physiological structures, diverse disease targets, limited
drug delivery space, distinctive barriers, and complicated biomechanical processes …
drug delivery space, distinctive barriers, and complicated biomechanical processes …
Fiber reinforced GelMA hydrogel to induce the regeneration of corneal stroma
B Kong, Y Chen, R Liu, X Liu, C Liu, Z Shao… - Nature …, 2020 - nature.com
Regeneration of corneal stroma has always been a challenge due to its sophisticated
structure and keratocyte-fibroblast transformation. In this study, we fabricate grid poly (ε …
structure and keratocyte-fibroblast transformation. In this study, we fabricate grid poly (ε …
Scaffold: a novel carrier for cell and drug delivery
Scaffolds are implants or injects, which are used to deliver cells, drugs, and genes into the
body. Different forms of polymeric scaffolds for cell/drug delivery are available:(1) a typical …
body. Different forms of polymeric scaffolds for cell/drug delivery are available:(1) a typical …
Designing scaffolds for corneal regeneration
Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …
millions of people. To treat these patients, researchers have been examining different …
Natural–origin polymers as carriers and scaffolds for biomolecules and cell delivery in tissue engineering applications
PB Malafaya, GA Silva, RL Reis - Advanced drug delivery reviews, 2007 - Elsevier
The present paper intends to overview a wide range of natural–origin polymers with special
focus on proteins and polysaccharides (the systems more inspired on the extracellular …
focus on proteins and polysaccharides (the systems more inspired on the extracellular …
Fibrin: a versatile scaffold for tissue engineering applications
TAE Ahmed, EV Dare, M Hincke - Tissue Engineering Part B …, 2008 - liebertpub.com
Tissue engineering combines cell and molecular biology with materials and mechanical
engineering to replace damaged or diseased organs and tissues. Fibrin is a critical blood …
engineering to replace damaged or diseased organs and tissues. Fibrin is a critical blood …
A review of three-dimensional in vitro tissue models for drug discovery and transport studies
NT Elliott, FAN Yuan - Journal of pharmaceutical sciences, 2011 - Elsevier
The use of animal models in drug discovery studies presents issues with feasibility and
ethical concerns. To address these limitations, in vitro tissue models have been developed …
ethical concerns. To address these limitations, in vitro tissue models have been developed …
Corneal bioprinting utilizing collagen‐based bioinks and primary human keratocytes
DF Duarte Campos, M Rohde, M Ross… - … Research Part A, 2019 - Wiley Online Library
Corneal transplantation is the treatment of choice for patients with advanced corneal
diseases. However, the outcome may be affected by graft rejection, high associated costs …
diseases. However, the outcome may be affected by graft rejection, high associated costs …
Cell encapsulation using biopolymer gels for regenerative medicine
NC Hunt, LM Grover - Biotechnology letters, 2010 - Springer
There has been a consistent increase in the mean life expectancy of the population of the
developed world over the past century. Healthy life expectancy, however, has not increased …
developed world over the past century. Healthy life expectancy, however, has not increased …