The design, synthesis and property characterization of new functional materials has
garnered interest in a variety of fields. Materials that are capable of recognizing and binding …

Co-crystallization is the supramolecular phenomenon of aggregation of two or more different
chemical entities in a crystalline lattice through non-covalent interactions. It encompasses …

As halogen bonds gain prevalence in supramolecular synthesis and materials chemistry, it
has become necessary to examine more closely how such interactions compete with or …

Pharmaceutical co-crystals present an opportunity to improve the solubility of conventional
active pharmaceutical ingredients (APIs). Despite advances in co-crystal screening, the …

Curcumin is a pharmaceutically viable ingredient derived from the rhizome of the Indian
spice turmeric (Curcuma longa). However, curcumin suffers from poor water solubility, which …

Cocrystal screening of hesperetin with certain countermolecules generated highly soluble
noncovalent derivatives in the form of eutectics, instead of expected cocrystals. As adhesive …

Multicomponent crystalline solid forms (salts, cocrystals and eutectics) are a promising
means of enhancing the dissolution behavior of poorly soluble drugs. The present study …

Combinational therapy has become increasingly popular in recent times due to various
advantages like greater therapeutic effect, reduced number of prescriptions, lower …

The cocrystallization approach has been applied to modify the poor solubility profile of the
biologically active 1, 2, 4-thiadiazole derivative (TDZ). Extensive cocrystal screening with a …

The multiparameter model comprising 1D and 2D QSPR/QSAR descriptors was proposed
and validated for phenolic acid binary systems. This approach is based on the optimization …