Epigenetic regulation of melanogenesis

S Zhou, H Zeng, J Huang, L Lei, X Tong, S Li… - Ageing research …, 2021 - Elsevier
Melanogenesis is a complex process in which melanin is synthesized in melanocytes and
transported to keratinocytes, which involves multiple genes and signaling pathways …

Intrinsic and extrinsic regulation of human skin melanogenesis and pigmentation

C Serre, V Busuttil, JM Botto - International journal of cosmetic …, 2018 - Wiley Online Library
In human skin, melanogenesis is a tightly regulated process. Indeed, several extracellular
signals are transduced via dedicated signalling pathways and mostly converge to MITF, a …

Recent progress in melasma pathogenesis

AY Lee - Pigment cell & melanoma research, 2015 - Wiley Online Library
Melasma is a common skin pigmentation condition. Given therapeutic difficulty as one of the
biggest concerns, understanding of the etiology and pathogenesis of melasma becomes …

[HTML][HTML] microRNAs in the Regulation of Melanogenesis

Y Hushcha, I Blo, L Oton-Gonzalez, GD Mauro… - International Journal of …, 2021 - mdpi.com
Melanogenesis is the process leading to the synthesis of melanin, the main substance that
influences skin color and plays a pivotal role against UV damage. Altered melanogenesis is …

Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells

M Vitiello, A Tuccoli, R D'Aurizio, S Sarti… - …, 2017 - pmc.ncbi.nlm.nih.gov
Despite increasing amounts of experimental evidence depicting the involvement of non-
coding RNAs in cancer, the study of BRAFV600E-regulated genes has thus far focused …

A comprehensive review of mammalian pigmentation: Paving the way for innovative hair colour-changing cosmetics

B Fernandes, A Cavaco-Paulo, T Matamá - Biology, 2023 - mdpi.com
Simple Summary The frequency of use of permanent hair dyes to change natural colour are
associated with fibre damage and with an increased risk of serious health problems. The …

Investigating melanogenesis-related microRNAs as disease biomarkers in vitiligo

HY Abdallah, NR Abdelhamid, EA Mohammed… - Scientific Reports, 2022 - nature.com
Vitiligo is considered a disabling disease that affects physical, social, psychological, and
occupational aspects of an individual's quality of life. The search for non-invasive and …

Micro RNA s in melanocyte and melanoma biology

M Mione, A Bosserhoff - Pigment cell & melanoma research, 2015 - Wiley Online Library
The importance of micro RNA s as key molecular components of cellular processes is now
being recognized. Recent reports have shown that micro RNA s regulate processes as …

MicroRNA-155 is Dysregulated in the Skin of Patients with Vitiligo and Inhibits Melanogenesis-associated Genes in Melanocytes and Keratinocytes.

L Šahmatova, S Tankov, E Prans… - Acta dermato …, 2016 - search.ebscohost.com
Little is known about the functions of microRNAs (miRNAs) in skin pigmentation disorders.
The aim of this study was to investigate the expression and potential role of miRNAs in …

Study on the mechanism of miR‐125b‐5p affecting melanocyte biological behavior and melanogenesis in vitiligo through regulation of MITF

X Wang, Y Wu, P Du, L Xu, Y Chen, J Li, X Pan… - Disease …, 2022 - Wiley Online Library
Objective. The goal was to confirm the mechanism by which miR‐125b‐5p influences
melanocyte biological behavior and melanogenesis in vitiligo by regulating MITF. Methods …