Quality by Design for enabling RNA platform production processes

S Daniel, Z Kis, C Kontoravdi, N Shah - Trends in biotechnology, 2022 - cell.com
RNA-based products have emerged as one of the most promising and strategic
technologies for global vaccination, infectious disease control, and future therapy …

Overview on LNP-mRNA encapsulation unit operation: Mixing technologies, scalability, and influence of formulation & process parameters on physico-chemical …

L Hourdel, N Lebaz, F Peral, M Ripoll… - International Journal of …, 2025 - Elsevier
Nanoparticles carrying active drug substances have been used since the 70′ s and have
undergone numerous improvements since then. Nowadays, the latest generation of …

Optimization of a Micromixer with Automatic Differentiation

J Jeßberger, JE Marquardt, L Heim, J Mangold… - Fluids, 2022 - mdpi.com
As micromixers offer the cheap and simple mixing of fluids and suspensions, they have
become a key device in microfluidics. Their mixing performance can be significantly …

Study on mass transfer in large-aspect-ratio micromixer with continuous dual splitting and recombination, and inclined ridges

L Han, J Yue, L Qin, Y Qu, D Zhou, Y Li - … Journal of Heat and Mass Transfer, 2025 - Elsevier
Micromixers are critical components within microfluidic systems, known for their outstanding
mass and heat transfer capabilities. However, during the scale-up, micromixers with large …

Determination of micromixing times in commercially available continuous-flow mixers: evaluation of the incorporation and interaction by exchange with the mean …

JHA Schuurmans, M Peeters, M Dorbec… - Journal of Flow …, 2024 - Springer
To understand and predict the effect of mixing in a mixer or reactor, characterization is
essential. The Villermaux-Dushman system of competitive parallel reactions is one of the …

Mechanical Design and Analysis of New Staircase Climbing Hand Truck

MI Ishak, DF Pailin - Advanced and Sustainable …, 2023 - ejournal.unimap.edu.my
The transportation of goods on a staircase could give challenges to the users, especially
those stay in a high-rise building particularly when the elevators are not in service. There is …

Mechanical Design and Analysis of Medical Gloves Remover

MI Ishak, MDJ Sikam… - Malaysian Journal of …, 2023 - ejournal.unimap.edu.my
Medical gloves play a pivotal role in ensuring clinical and hospital safety, as well as
optimizing performance. Throughout the medical field, it has been traditionally understood …