As resident macrophages of the central nervous system (CNS), microglia are associated
with diverse functions essential to the develo** and adult brain during homeostasis and …

Microglia were first recognized as a distinct cell population in the CNS one century ago. For
a long time, they were primarily considered to be phagocytes responsible for removing …

INTRODUCTION Under homeostasis, the central nervous system (CNS) hosts microglia
(MG) and CNS-associated macrophages (CAMs). During experimental autoimmune …

Microglia have critical roles not only in neural development and homeostasis, but also in
neurodegenerative and neuroinflammatory diseases of the central nervous system,,–. These …

Microglia are the resident macrophages of the central nervous system (CNS). They have
important physiological functions in maintaining tissue homeostasis but also contribute to …

Perivascular, subdural meningeal and choroid plexus macrophages are non-parenchymal
macrophages that mediate immune responses at brain boundaries. Although the origin of …

The CNS is protected by the immune system, including cells that reside directly within the
CNS and help to ensure proper neural function, as well as cells that traffic into the CNS with …

Myeloid cells in the central nervous system (CNS) represent a heterogeneous class of
innate immune cells that contribute to the maintenance of tissue homeostasis differentially …

Mononuclear phagocytic cells in the CNS used to be defined according to their anatomical
location and surface marker expression. Recently, this concept has been challenged by the …

Macrophages are myeloid immune cells that are strategically positioned throughout the
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …