[HTML][HTML] Regulation of innate immunity by Nrf2
D van der Horst, ME Carter-Timofte… - Current Opinion in …, 2022 - Elsevier
The transcription factor Nuclear factor erythroid 2-related factor 2 (Nrf2) has been mainly
investigated as a regulator of redox homeostasis. However, research over the past years …
investigated as a regulator of redox homeostasis. However, research over the past years …
Vascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants
JM Cook-Mills, ME Marchese… - Antioxidants & redox …, 2011 - liebertpub.com
The endothelium is immunoregulatory in that inhibiting the function of vascular adhesion
molecules blocks leukocyte recruitment and thus tissue inflammation. The function of …
molecules blocks leukocyte recruitment and thus tissue inflammation. The function of …
The role of protein tyrosine phosphatase 1B (PTP1B) in the pathogenesis of type 2 diabetes mellitus and its complications
Insulin resistance, the most important characteristic of the type 2 diabetes mellitus (T2DM), is
mostly caused by impairment in the insulin receptor (IR) signal transduction pathway …
mostly caused by impairment in the insulin receptor (IR) signal transduction pathway …
Insulin resistance and atherosclerosis
CF Semenkovich - The Journal of clinical investigation, 2006 - Am Soc Clin Investig
Considerable evidence supports the association between insulin resistance and vascular
disease, and this has led to wide acceptance of the clustering of hyperlipidemia, glucose …
disease, and this has led to wide acceptance of the clustering of hyperlipidemia, glucose …
PTP1B: a simple enzyme for a complex world
M Feldhammer, N Uetani… - Critical reviews in …, 2013 - Taylor & Francis
Our understanding of the fundamental regulatory roles that tyrosine phosphatases play
within cells has advanced significantly in the last two decades. Out-dated ideas that tyrosine …
within cells has advanced significantly in the last two decades. Out-dated ideas that tyrosine …
Protein tyrosine phosphatase function: the substrate perspective
It is now well established that the members of the PTP (protein tyrosine phosphatase)
superfamily play critical roles in fundamental biological processes. Although there has been …
superfamily play critical roles in fundamental biological processes. Although there has been …
Leishmania GP63 Alters Host Signaling Through Cleavage-Activated Protein Tyrosine Phosphatases
With more than 12 million people affected worldwide, 2 million new cases occurring per
year, and the rapid emergence of drug resistance and treatment failure, leishmaniasis is an …
year, and the rapid emergence of drug resistance and treatment failure, leishmaniasis is an …
Protein-Tyrosine Phosphatase 1B Is Required for HER2/Neu–Induced Breast Cancer
M Bentires-Alj, BG Neel - Cancer research, 2007 - AACR
The protein-tyrosine phosphatase 1B (PTP1B; PTPN1) is an important regulator of
mammalian metabolism and also helps control signaling by growth factors, cytokines, and …
mammalian metabolism and also helps control signaling by growth factors, cytokines, and …
[HTML][HTML] PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils
Acute lung injury (ALI) can cause acute respiratory distress syndrome (ARDS), a lethal
condition with limited treatment options and currently a common global cause of death due …
condition with limited treatment options and currently a common global cause of death due …
High-throughput proteomic profiling of the fish liver following bacterial infection
Background High-throughput proteomics was used to determine the role of the fish liver in
defense responses to bacterial infection. This was done using a rainbow trout …
defense responses to bacterial infection. This was done using a rainbow trout …