Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics

S Simpson, MD Dunning, S de Brot… - Acta Veterinaria …, 2017 - Springer
Osteosarcoma (OSA) is a rare cancer in people. However OSA incidence rates in dogs are
27 times higher than in people. Prognosis in both species is relatively poor, with 5 year OSA …

Translation of new cancer treatments from pet dogs to humans

M Paoloni, C Khanna - Nature Reviews Cancer, 2008 - nature.com
Naturally occurring cancers in pet dogs and humans share many features, including
histological appearance, tumour genetics, molecular targets, biological behaviour and …

Cancer chemotherapy

DL Gustafson, RL Page - Withrow & MacEwen's Small Anımal …, 2012 - books.google.com
The use of chemical elixirs for the treatment of cancer can be traced through the medicinal
customs and practices of a number of cultures. 1 The modern use of pharmacologic agents …

Cisplatin: a review of toxicities and therapeutic applications

K Barabas, R Milner, D Lurie… - … and comparative oncology, 2008 - Wiley Online Library
Cisplatin is a platinum chemotherapeutic used in a variety of malignancies. The
antineoplastic activity occurs from DNA cross‐links and adducts, in addition to the …

Immunotherapy with a HER2-Targeting Listeria Induces HER2-Specific Immunity and Demonstrates Potential Therapeutic Effects in a Phase I Trial in Canine …

NJ Mason, JS Gnanandarajah, JB Engiles… - Clinical Cancer …, 2016 - aacrjournals.org
Abstract Purpose: Recombinant Listeria vaccines induce tumor-specific T-cell responses
that eliminate established tumors and prevent metastatic disease in murine cancer models …

What do we know about canine osteosarcoma treatment?–review

M Szewczyk, R Lechowski, K Zabielska - Veterinary research …, 2015 - Springer
Osteosarcoma (OSA) is the most common type of bone tumors in dogs, which has high
metastasis ability. 80% of dogs with OSA die due to lung metastasis. As a result its treatment …

Biology, diagnosis and treatment of canine appendicular osteosarcoma: similarities and differences with human osteosarcoma

E Morello, M Martano, P Buracco - The veterinary journal, 2011 - Elsevier
Osteosarcoma (OSA) is the most common primary bone tumour in dogs. The appendicular
locations are most frequently involved and large to giant breed dogs are commonly affected …

Tumours of the skeletal system

WS Dernell - BSAVA manual of canine and feline oncology, 2011 - bsavalibrary.com
Osteosarcoma is by far the most common primary bone tumour in dogs, accounting for up to
85% of malignancies originating in the skeleton. This chapter covers osteosarcoma in dogs; …

Comparison of carboplatin and doxorubicin‐based chemotherapy protocols in 470 dogs after amputation for treatment of appendicular osteosarcoma

LE Selmic, JH Burton, DH Thamm… - Journal of Veterinary …, 2014 - Wiley Online Library
Background Many chemotherapy protocols have been reported for treatment of canine
appendicular osteosarcoma (OSA), but outcome comparisons in a single population are …

Comparative biology of human and canine osteosarcoma

F Mueller, B Fuchs, B Kaser-Hotz - Anticancer research, 2007 - ar.iiarjournals.org
Dogs with osteosarcoma provide an important model for the same disease in humans. In this
report, the comparative nature of human and canine osteosarcoma including incidence and …