A virtual patient simulation modeling the neural and perceptual effects of human visual cortical stimulation, from pulse trains to percepts
I Fine, GM Boynton - Scientific Reports, 2024 - nature.com
The field of cortical sight restoration prostheses is making rapid progress with three clinical
trials of visual cortical prostheses underway. However, as yet, we have only limited insight …
trials of visual cortical prostheses underway. However, as yet, we have only limited insight …
Avoidance of axonal stimulation with sinusoidal epiretinal stimulation
Objective. Neuromodulation, particularly electrical stimulation, necessitates high spatial
resolution to achieve artificial vision with high acuity. In epiretinal implants, this is hindered …
resolution to achieve artificial vision with high acuity. In epiretinal implants, this is hindered …
Decoding dynamic visual scenes across the brain hierarchy
Y Chen, P Beech, Z Yin, S Jia, J Zhang… - PLOS Computational …, 2024 - journals.plos.org
Understanding the computational mechanisms that underlie the encoding and decoding of
environmental stimuli is a crucial investigation in neuroscience. Central to this pursuit is the …
environmental stimuli is a crucial investigation in neuroscience. Central to this pursuit is the …
Precise control of neural activity using dynamically optimized electrical stimulation
Neural implants have the potential to restore lost sensory function by electrically evoking the
complex naturalistic activity patterns of neural populations. However, it can be difficult to …
complex naturalistic activity patterns of neural populations. However, it can be difficult to …
Understanding responses to multi-electrode epiretinal stimulation using a biophysical model
Objective. Neural interfaces are designed to evoke specific patterns of electrical activity in
populations of neurons by stimulating with many electrodes. However, currents passed …
populations of neurons by stimulating with many electrodes. However, currents passed …
[HTML][HTML] Virtual Human Retina: Simulating Neural Signalling, Degeneration, and Responses to Electrical Stimulation
Introduction Current brain-based visual prostheses pose significant challenges impeding
adoption such as the necessarily complex surgeries and occurrence of more substantial …
adoption such as the necessarily complex surgeries and occurrence of more substantial …
Comparison of modulation efficiency between normal and degenerated primate retina
With electrical stimulation, retinal prostheses bypass dysfunctional photoreceptors and
activate the surviving bipolar or retinal ganglion cells (RGCs). Therefore, the effective …
activate the surviving bipolar or retinal ganglion cells (RGCs). Therefore, the effective …
Spike sorting in the presence of stimulation artifacts: a dynamical control systems approach
Objective. Bi-directional electronic neural interfaces, capable of both electrical recording and
stimulation, communicate with the nervous system to permit precise calibration of electrical …
stimulation, communicate with the nervous system to permit precise calibration of electrical …
Short pulse epiretinal stimulation allows focal activation of retinal ganglion cells
LX Koppenwallner, G Zeck… - IEEE Transactions on …, 2025 - ieeexplore.ieee.org
Epiretinal implants suffer from a lack of spatial resolution, which is greatly influenced by the
undesired co-activation of distal cells with their axons passing close to targeted somas …
undesired co-activation of distal cells with their axons passing close to targeted somas …
Deep Learning for Visual Neuroprosthesis
The visual pathway involves complex networks of cells and regions which contribute to the
encoding and processing of visual information. While some aspects of visual perception are …
encoding and processing of visual information. While some aspects of visual perception are …