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[HTML][HTML] Biomarkers in cancer detection, diagnosis, and prognosis
Biomarkers are vital in healthcare as they provide valuable insights into disease diagnosis,
prognosis, treatment response, and personalized medicine. They serve as objective …
prognosis, treatment response, and personalized medicine. They serve as objective …
[HTML][HTML] The Evolving Paradigm of Antibody–Drug Conjugates Targeting the ErbB/HER Family of Receptor Tyrosine Kinases
Current therapies targeting the human epidermal growth factor receptor (HER) family,
including monoclonal antibodies (mAbs) and tyrosine kinase inhibitors (TKIs), are limited by …
including monoclonal antibodies (mAbs) and tyrosine kinase inhibitors (TKIs), are limited by …
[HTML][HTML] Prospective Molecular Targets for Natural Killer Cell Immunotherapy against Glioblastoma Multiforme
LC Cooksey, DC Friesen, ED Mangan, PA Mathew - Cells, 2024 - pmc.ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) is the most common type of primary malignant brain tumor
and has a dismal overall survival rate. To date, no GBM therapy has yielded successful …
and has a dismal overall survival rate. To date, no GBM therapy has yielded successful …
The Icarian flight of antibody-drug conjugates: target selection amidst complexity and tackling adverse impacts
H Liu, H Zeng, X Qin, W Ning, L Xu, S Yang, X Liu… - Protein & …, 2025 - academic.oup.com
Antibody-drug conjugates (ADCs) represent a promising class of targeted cancer
therapeutics that combine the specificity of monoclonal antibodies with the potency of …
therapeutics that combine the specificity of monoclonal antibodies with the potency of …
Deguelin Restores Paclitaxel Sensitivity in Paclitaxel-Resistant Ovarian Cancer Cells via Inhibition of the EGFR Signaling Pathway
S Bae, S Bae, HS Kim, YJ Lim, G Kim… - Cancer Management …, 2024 - Taylor & Francis
Background Ovarian cancer is one of women's malignancies with the highest mortality
among gynecological cancers. Paclitaxel is used in first-line ovarian cancer chemotherapy …
among gynecological cancers. Paclitaxel is used in first-line ovarian cancer chemotherapy …
[HTML][HTML] Prognostic and Predictive Roles of HER2 Status in Non-Breast and Non-Gastroesophageal Carcinomas
Simple Summary Over the past years, the introduction of various anti-HER2 therapies has
significantly improved the outcome for patients with HER2-positive breast and …
significantly improved the outcome for patients with HER2-positive breast and …
[HTML][HTML] Structural Basis of Activity of HER2-Targeting Construct Composed of DARPin G3 and Albumin-Binding Domains
AG Konshina, EV Bocharov… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Non-immunoglobulin-based scaffold proteins (SPs) represent one of the key therapeutic
target-specific and high-affinity binders in modern medicine. Among their cellular targets are …
target-specific and high-affinity binders in modern medicine. Among their cellular targets are …
[PDF][PDF] Men's gallbladder cancer: epidemiology, prevention, and treatment strategies
Y Pyo, KH Kwon - Journal of Men's Health, 2024 - oss.jomh.org
Herein, it was aimed to review the epidemiology, prevention, and treatment strategies for
men's gallbladder cancer (GBC).“Gallbladder cancer” and “GBC” were searched in four …
men's gallbladder cancer (GBC).“Gallbladder cancer” and “GBC” were searched in four …
Ферменти метаболізму естрогенів та прогестеронів їх рецептори при раку молочної залози
МІ Пилипчак - 2024 - dspace.zsmu.edu.ua
Мета і задачі: дослідження особливостей клінічного перебігу РМЗ, експресії ER i PR,
акивність ароматази (АА), стероїд сульфатази (STS) і 17-бета гідроксистероїд …
акивність ароматази (АА), стероїд сульфатази (STS) і 17-бета гідроксистероїд …
[PDF][PDF] Obtención de los dominios extracelulares del HER1 y el HER2 acoplados a etiqueta de histidina para su empleo como antígenos de una vacuna específica por …
DCBS Ramírez - 2024 - fototeca.uh.cu
La estrecha relación existente entre los receptores para el factor de crecimiento epidérmico
humanos HER1 y HER2 (del inglés,“human epidermal growth factor receptors 1-2”) y la …
humanos HER1 y HER2 (del inglés,“human epidermal growth factor receptors 1-2”) y la …