Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development

B Meduri, GV Pujar, TDA Kumar, HS Akshatha… - European Journal of …, 2021 - Elsevier
Lysophosphatidic acid (LPA) activates six LPA receptors (LPAR 1-6) and regulates various
cellular activities such as cell proliferation, cytoprotection, and wound healing. Many studies …

Monitoring ligand-induced changes in receptor conformation with NanoBiT conjugated nanobodies

M Soave, R Heukers, B Kellam, J Woolard, MJ Smit… - bioRxiv, 2020 - biorxiv.org
Camelid single-domain antibody fragments (nanobodies) offer the specificity of an antibody
in a single 15kDa immunoglobulin domain. Their small size allows for easy genetic …