Safety, efficacy, and cost-effectiveness of tranexamic acid in orthopedic surgery
ZX Lin, SK Woolf - Orthopedics, 2016 - journals.healio.com
Perioperative bleeding and postsurgical hemorrhage are common in invasive surgical
procedures, including orthopedic surgery. Tranexamic acid (TXA) is a pharmacologic agent …
procedures, including orthopedic surgery. Tranexamic acid (TXA) is a pharmacologic agent …
Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and …
J Poeran, R Rasul, S Suzuki, T Danninger… - Bmj, 2014 - bmj.com
Objective To determine the effectiveness and safety of perioperative tranexamic acid use in
patients undergoing total hip or knee arthroplasty in the United States. Design Retrospective …
patients undergoing total hip or knee arthroplasty in the United States. Design Retrospective …
Efficacy and safety of single-and double-dose intravenous tranexamic acid in hip and knee arthroplasty: a systematic review and meta-analysis
YZ Yang, QH Cheng, AR Zhang, X Yang… - Journal of orthopaedic …, 2023 - Springer
Objective With the increasing prevalence of osteoarthritis of the hip and knee, total joint
replacement, the end-stage treatment, provides pain relief and restoration of function, but is …
replacement, the end-stage treatment, provides pain relief and restoration of function, but is …
Tranexamic acid administration in primary total hip arthroplasty: a randomized controlled trial of intravenous combined with topical versus single-dose intravenous …
Z Yi, S Bin, Y **g, Z Zongke, K Pengde, P Fuxing - JBJS, 2016 - journals.lww.com
Background: The use of tranexamic acid (TXA) in primary total hip arthroplasty is well
documented. However, considering the potential side effects, including deep vein …
documented. However, considering the potential side effects, including deep vein …
Intravenous versus intra-articular tranexamic acid in total knee arthroplasty: a double-blinded randomised controlled noninferiority trial
Background Despite the proven efficacy of both intravenous (IV) and intra-articular (IA)
tranexamic acid (TXA) in reducing blood loss during total knee arthroplasty (TKA), the ideal …
tranexamic acid (TXA) in reducing blood loss during total knee arthroplasty (TKA), the ideal …
Tranexamic acid decreases blood loss after total shoulder arthroplasty
RJ Friedman, E Gordon, RB Butler, L Mock… - Journal of shoulder and …, 2016 - Elsevier
Background Tranexamic acid (TXA) significantly decreases blood loss and transfusion rates
after total hip and total knee arthroplasty. The purpose of this study was to determine the …
after total hip and total knee arthroplasty. The purpose of this study was to determine the …
Process improvement project using tranexamic acid is cost-effective in reducing blood loss and transfusions after total hip and total knee arthroplasty
HA Demos, ZX Lin, WR Barfield, SH Wilson… - The Journal of …, 2017 - Elsevier
Background Tranexamic acid (TXA) has been associated with decreased blood loss and
transfusion after total hip arthroplasty (THA) and total knee arthroplasty (TKA). The purpose …
transfusion after total hip arthroplasty (THA) and total knee arthroplasty (TKA). The purpose …
Tranexamic acid in hip fracture patients: a protocol for a randomised, placebo controlled trial on the efficacy of tranexamic acid in reducing blood loss in hip fracture …
EB Gausden, MR Garner, SJ Warner, A Levack… - BMJ open, 2016 - bmjopen.bmj.com
Introduction There is a high incidence of blood transfusion following hip fractures in elderly
patients. Tranexamic acid (TXA) has proven efficacy in decreasing blood loss in general …
patients. Tranexamic acid (TXA) has proven efficacy in decreasing blood loss in general …
Low risk of thromboembolic events after routine administration of tranexamic acid in hip and knee arthroplasty
RV Madsen, CS Nielsen, T Kallemose, H Husted… - The Journal of …, 2017 - Elsevier
Background The blood-conserving effect of intravenous (IV) tranexamic acid (TXA) is well-
documented for total hip arthroplasty (THA) and total knee arthroplasty (TKA). However, the …
documented for total hip arthroplasty (THA) and total knee arthroplasty (TKA). However, the …
Similar thromboprophylaxis with rivaroxaban and low molecular weight heparin but fewer hemorrhagic complications with combined intra-articular and intravenous …
PK Karampinas, PD Megaloikonomos… - European journal of …, 2019 - Springer
Purpose To evaluate the efficacy of the combined intravenous and intra-articular
administration of tranexamic acid (TXA) to control the collateral effects and complications of …
administration of tranexamic acid (TXA) to control the collateral effects and complications of …