Obesity and its related health complications is a major problem worldwide. Hypothalamus
and their signalling molecules play a critical role in the intervening and coordination with …

The mechanisms for controlling food intake involve mainly an interplay between gut, brain,
and adipose tissue (AT), among the major organs. Parasympathetic, sympathetic, and other …

Metabolic syndrome (MetS) is a clustering of several cardiovascular risk factors that include:
obesity, dyslipidemia, hypertension and high blood glucose, and often requires multidrug …

Objectives Despite advances in our understanding of metabolic syndrome (MetS) and the
treatment of each of its components separately, currently there is no single therapy approved …

Endothelial dysfunction (ED) is a core pathophysiological process. The abnormal response
of vascular endothelial (VE) cells to risk factors can lead to systemic consequences. ED …

Neuropeptide Y (NPY) in noradrenergic neurons plays an important role in modulating the
release and effects of catecholamines in a prolonged stress response. Among other …

Variants in the neuropeptide Y (NPY) gene have been associated with obesity and its traits.
The objective of the present study was to evaluate the association of single nucleotide …

Maternal serum activin A levels are elevated in women with preeclampsia. To explore
whether this could be due, at least in part, to increased production by the gestational tissues …

Many physiological pathways are involved in appetite, food intake, and the maintenance of
energy homeostasis. In particular, neuropeptides within the central nervous system have …

Neuropeptide Y (NPY) plays an important role in the regulation of energy homeostasis in the
level of central and sympathetic nervous systems (SNSs). Genetic silencing of peripheral Y2 …