Macrophages are myeloid immune cells that are strategically positioned throughout the
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …

The intestine contains the largest pool of macrophages in the body which are essential for
maintaining mucosal homeostasis in the face of the microbiota and the constant need for …

Secretory immunoglobulin A (sIgA) plays an important role in gut barrier protection by
sha** the resident microbiota community, restricting the growth of bacterial pathogens and …

Macrophages in the healthy intestine are highly specialized and usually respond to the gut
microbiota without provoking an inflammatory response. A breakdown in this tolerance leads …

Intestinal peristalsis is a dynamic physiologic process influenced by dietary and microbial
changes. It is tightly regulated by complex cellular interactions; however, our understanding …

While conventional pathogenic protists have been extensively studied, there is an
underappreciated constitutive protist microbiota that is an integral part of the vertebrate …

How commensal microbiota contributes to immune cell homeostasis at barrier surfaces is
poorly understood. Lamina propria (LP) T helper 17 (Th17) cells participate in mucosal …

Introduction The gastrointestinal tract is colonized by an extraordinarily large number of
commensal microbes and is constantly exposed to ingested antigens and potential …

Commensal bacteria are necessary for the development and maintenance of a healthy
immune system. Harnessing the ability of microbiota to affect host immunity is considered an …

Dendritic cells (DCs), monocytes, and macrophages are closely related phagocytes that
share many phenotypic features and, in some cases, a common developmental origin …