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[HTML][HTML] The involvement of the Wnt/β-catenin signaling cascade in fibrosis progression and its therapeutic targeting by relaxin
DVN Somanader, P Zhao, RE Widdop… - Biochemical …, 2024 - Elsevier
Organ scarring, referred to as fibrosis, results from a failed wound-healing response to
chronic tissue injury and is characterised by the aberrant accumulation of various …
chronic tissue injury and is characterised by the aberrant accumulation of various …
TGF-β-based therapies for treating ocular surface disorders
The cornea is continuously exposed to injuries, ranging from minor scratches to deep
traumas. An effective healing mechanism is crucial for the cornea to restore its structure and …
traumas. An effective healing mechanism is crucial for the cornea to restore its structure and …
Thyroid-associated ophthalmopathy: the role of oxidative stress
C Ma, H Li, S Lu, X Li - Frontiers in Endocrinology, 2024 - frontiersin.org
Thyroid-associated ophthalmopathy (TAO) is an autoimmune condition affecting the eyes,
characterized by proptosis, extraocular muscle involvement, and in severe cases, vision …
characterized by proptosis, extraocular muscle involvement, and in severe cases, vision …
Botulinum neurotoxin induces neurotoxic microglia mediated by exogenous inflammatory responses
Botulinum neurotoxin serotype A (BoNT/A) is widely used in therapeutics and cosmetics.
The effects of multi‐dosed BoNT/A treatment are well documented on the peripheral nervous …
The effects of multi‐dosed BoNT/A treatment are well documented on the peripheral nervous …
Thyroid-associated ophthalmopathy and ferroptosis: a review of pathological mechanisms and therapeutic strategies
C Ma, H Li, S Lu, X Li - Frontiers in Immunology, 2024 - frontiersin.org
Thyroid-associated ophthalmopathy (TAO) is an inflammatory orbital disease associated
with autoimmune thyroid disorders. Owing to the ambiguous nature of the pathogenesis …
with autoimmune thyroid disorders. Owing to the ambiguous nature of the pathogenesis …
[HTML][HTML] A review of pathophysiology and therapeutic strategies targeting TGF-β in Graves' ophthalmopathy
TGF-β plays a pivotal role in the pathogenesis of GO by promoting orbital tissue remodeling
and fibrosis. This process involves the stimulation of orbital fibroblasts, leading to …
and fibrosis. This process involves the stimulation of orbital fibroblasts, leading to …
Low-level laser therapy in the treatment of autoimmune thyroiditis
N Hossein-Khannazer, MK Arki… - Journal of Lasers in …, 2022 - pmc.ncbi.nlm.nih.gov
Introduction: Autoimmune thyroiditis (AIT) is an autoimmune disorder that is characterized by
thyroid gland dysfunction. Low-level laser therapy (LLLT), as a safe and non-invasive …
thyroid gland dysfunction. Low-level laser therapy (LLLT), as a safe and non-invasive …
Exposure of Akwesasne Mohawk women to polychlorinated biphenyls and hexachlorobenzene is associated with increased serum levels of thyroid peroxidase …
Persistent organic pollutants (POPs) including polychlorinated biphenyls (PCBs),
hexachlorobenzene (HCB), and dichlorodiphenyltrichloroethane (p, p'-DDT) were reported …
hexachlorobenzene (HCB), and dichlorodiphenyltrichloroethane (p, p'-DDT) were reported …
Evaluation of epithelial–mesenchymal transition markers in autoimmune thyroid diseases
P Sacristán-Gómez, A Serrano-Somavilla… - International Journal of …, 2023 - mdpi.com
A state of chronic inflammation is common in organs affected by autoimmune disorders,
such as autoimmune thyroid diseases (AITD). Epithelial cells, such as thyroid follicular cells …
such as autoimmune thyroid diseases (AITD). Epithelial cells, such as thyroid follicular cells …
[HTML][HTML] Трансформирующий фактор роста β1 (TGF-β1) у пациентов с эндокринной офтальмопатией и болезнью Грейвса-предиктор эффективности лечения
НЮ Свириденко, ЕГ Бессмертная… - Медицинская …, 2022 - cyberleninka.ru
Существующие терапевтические подходы к лечению эндокринной офтальмопатии
(ЭОП) основываются на неспецифической иммуносупрессии глюкокортикоидами (ГК) и …
(ЭОП) основываются на неспецифической иммуносупрессии глюкокортикоидами (ГК) и …