Architecture of the dynamic fungal cell wall

NAR Gow, MD Lenardon - Nature Reviews Microbiology, 2023 - nature.com
The fungal cell wall is essential for growth and survival, and is a key target for antifungal
drugs and the immune system. The cell wall must be robust but flexible, protective and …

Candida albicans—The Virulence Factors and Clinical Manifestations of Infection

J Talapko, M Juzbašić, T Matijević, E Pustijanac… - Journal of Fungi, 2021 - mdpi.com
Candida albicans is a common commensal fungus that colonizes the oropharyngeal cavity,
gastrointestinal and vaginal tract, and healthy individuals' skin. In 50% of the population, C …

Candida parapsilosis Virulence and Antifungal Resistance Mechanisms: A Comprehensive Review of Key Determinants

J Branco, IM Miranda, AG Rodrigues - Journal of Fungi, 2023 - mdpi.com
Candida parapsilosis is the second most common Candida species isolated in Asia,
Southern Europe, and Latin America and is often involved in invasive infections that …

[HTML][HTML] Biofilm Formation in Medically Important Candida Species

Z Malinovská, E Čonková, P Váczi - Journal of Fungi, 2023 - mdpi.com
Worldwide, the number of infections caused by biofilm-forming fungal pathogens is very
high. In human medicine, there is an increasing proportion of immunocompromised patients …

Candida albicans and Candida glabrata: global priority pathogens

M Katsipoulaki, MHT Stappers… - Microbiology and …, 2024 - journals.asm.org
SUMMARY A significant increase in the incidence of Candida-mediated infections has been
observed in the last decade, mainly due to rising numbers of susceptible individuals …

Biocontrol yeasts: mechanisms and applications

FM Freimoser, MP Rueda-Mejia, B Tilocca… - World Journal of …, 2019 - Springer
Yeasts occur in all environments and have been described as potent antagonists of various
plant pathogens. Due to their antagonistic ability, undemanding cultivation requirements …

Invasive candidiasis: current clinical challenges and unmet needs in adult populations

A Soriano, PM Honore, P Puerta-Alcalde… - Journal of …, 2023 - academic.oup.com
Invasive candidiasis (IC) is a serious infection caused by several Candida species, and the
most common fungal disease in hospitals in high-income countries. Despite overall …

Candida albicans biofilms and polymicrobial interactions

NO Ponde, L Lortal, G Ramage, JR Naglik… - Critical reviews in …, 2021 - Taylor & Francis
Candida albicans is a common fungus of the human microbiota. While generally a harmless
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …

Drug-resistant fungi: an emerging challenge threatening our limited antifungal armamentarium

A Arastehfar, T Gabaldón, R Garcia-Rubio, JD Jenks… - Antibiotics, 2020 - mdpi.com
The high clinical mortality and economic burden posed by invasive fungal infections (IFIs),
along with significant agricultural crop loss caused by various fungal species, has resulted in …

Candida parapsilosis: from genes to the bedside

R Tóth, J Nosek, HM Mora-Montes… - Clinical microbiology …, 2019 - journals.asm.org
Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …