An immune origin of type 2 diabetes?

H Kolb, T Mandrup-Poulsen - Diabetologia, 2005 - Springer
Subclinical, low-grade systemic inflammation has been observed in patients with type 2
diabetes and in those at increased risk of the disease. This may be more than an …

Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention

A Badawi, A Klip, P Haddad, DEC Cole… - … syndrome and obesity …, 2010 - Taylor & Francis
Obesity is a major risk factor for type 2 diabetes mellitus (T2DM), which is a significant health
problem worldwide. Active disease is associated with low-grade chronic inflammation …

Bidirectional causal associations between type 2 diabetes and COVID‐19

H Cao, A Baranova, X Wei, C Wang… - Journal of Medical …, 2023 - Wiley Online Library
Observational studies have reported high comorbidity between type 2 diabetes (T2D) and
severe COVID‐19. However, the causality between T2D and COVID‐19 has yet to be …

Relationships between disease activity and serum and fecal biomarkers in patients with Crohn's disease

J Jones, EV Loftus Jr, R Panaccione, LS Chen… - Clinical …, 2008 - Elsevier
BACKGROUND & AIMS: The quantitative relationships between instruments and assays that
measure clinical, endoscopic, and biologic disease activity in patients with Crohn's disease …

Vitamin D and diabetes mellitus

LG Danescu, S Levy, J Levy - Endocrine, 2009 - Springer
Better understanding of the physiological role of the vitamin-D system, in particular its
potential effects on inflammatory and autoimmune conditions as well as on insulin secretion …

Genetic variation, C-reactive protein levels, and incidence of diabetes

A Dehghan, I Kardys, MPM de Maat, AG Uitterlinden… - …, 2007 - diabetesjournals.org
C-reactive protein (CRP) has been shown to be associated with type 2 diabetes, but whether
CRP has a causal role is not yet clear. We examined the association in the Rotterdam Study …

C-reactive protein gene polymorphisms, C-reactive protein blood levels, and cardiovascular disease risk

FG Hage, AJ Szalai - Journal of the American college of cardiology, 2007 - jacc.org
C-reactive protein (CRP), a blood marker of inflammation and a hallmark of the acute-phase
response, has been shown to be a powerful and specific predictor of cardiovascular event …

Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels

CS Carlson, SF Aldred, PK Lee, RP Tracy… - The American Journal of …, 2005 - cell.com
Elevated plasma levels of C-reactive protein (CRP), an inflammation-sensitive marker, have
emerged as an important predictor of future cardiovascular disease and metabolic …

Common genetic vulnerability to depressive symptoms and coronary artery disease: a review and development of candidate genes related to inflammation and …

JM McCaffery, N Frasure-Smith, MP Dubé… - Psychosomatic …, 2006 - journals.lww.com
Objective: Although it is well established that depressive symptoms are associated with
recurrent cardiac events among cardiac patients and novel cardiac events among …

Inflammation, Insulin Resistance, and Diabetes—Mendelian Randomization Using CRP Haplotypes Points Upstream

EJ Brunner, M Kivimäki, DR Witte, DA Lawlor… - PLoS …, 2008 - journals.plos.org
Background Raised C-reactive protein (CRP) is a risk factor for type 2 diabetes. According to
the Mendelian randomization method, the association is likely to be causal if genetic …