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Principles of regulatory T cell function
S Dikiy, AY Rudensky - Immunity, 2023 - cell.com
Regulatory T (Treg) cells represent a distinct lineage of cells of the adaptive immune system
indispensable for forestalling fatal autoimmune and inflammatory pathologies. The role of …
indispensable for forestalling fatal autoimmune and inflammatory pathologies. The role of …
RNA modifications: importance in immune cell biology and related diseases
L Cui, R Ma, J Cai, C Guo, Z Chen, L Yao… - Signal transduction and …, 2022 - nature.com
RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …
including generation, transportation, function, and metabolization, they act as critical …
Memory B cells
T Inoue, T Kurosaki - Nature Reviews Immunology, 2024 - nature.com
Recent advances in studies of immune memory in mice and humans have reinforced the
concept that memory B cells play a critical role in protection against repeated infections …
concept that memory B cells play a critical role in protection against repeated infections …
Role of B cells as antigen presenting cells
B cells have been long studied for their role and function in the humoral immune system.
Apart from generating antibodies and an antibody-mediated memory response against …
Apart from generating antibodies and an antibody-mediated memory response against …
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses
Adjuvants are critical for improving the quality and magnitude of adaptive immune
responses to vaccination. Lipid nanoparticle (LNP)-encapsulated nucleoside-modified …
responses to vaccination. Lipid nanoparticle (LNP)-encapsulated nucleoside-modified …
SARS-CoV-2 variants, vaccines, and host immunity
P Mistry, F Barmania, J Mellet, K Peta… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new beta coronavirus
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …
The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy
D Bruni, HK Angell, J Galon - Nature Reviews Cancer, 2020 - nature.com
Abstract The international American Joint Committee on Cancer/Union for International
Cancer Control (AJCC/UICC) tumour-node-metastasis (TNM) staging system provides the …
Cancer Control (AJCC/UICC) tumour-node-metastasis (TNM) staging system provides the …
Interaction between microbiota and immunity in health and disease
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …
development and function includes multifold interactions in homeostasis and disease. The …
[HTML][HTML] Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19
We present an integrated analysis of the clinical measurements, immune cells, and plasma
multi-omics of 139 COVID-19 patients representing all levels of disease severity, from serial …
multi-omics of 139 COVID-19 patients representing all levels of disease severity, from serial …
[HTML][HTML] Loss of Bcl-6-expressing T follicular helper cells and germinal centers in COVID-19
Humoral responses in coronavirus disease 2019 (COVID-19) are often of limited durability,
as seen with other human coronavirus epidemics. To address the underlying etiology, we …
as seen with other human coronavirus epidemics. To address the underlying etiology, we …