Human genetics and malaria resistance
Malaria has been the pre-eminent cause of early mortality in many parts of the world
throughout much of the last five thousand years and, as a result, it is the strongest force for …
throughout much of the last five thousand years and, as a result, it is the strongest force for …
Programmable interactions with biomimetic DNA linkers at fluid membranes and interfaces
At the heart of the structured architecture and complex dynamics of biological systems are
specific and timely interactions operated by biomolecules. In many instances, biomolecular …
specific and timely interactions operated by biomolecules. In many instances, biomolecular …
Common host variation drives malaria parasite fitness in healthy human red cells
The replication of Plasmodium falciparum parasites within red blood cells (RBCs) causes
severe disease in humans, especially in Africa. Deleterious alleles like hemoglobin S are …
severe disease in humans, especially in Africa. Deleterious alleles like hemoglobin S are …
Actomyosin forces and the energetics of red blood cell invasion by the malaria parasite Plasmodium falciparum
TCA Blake, S Haase, J Baum - PLoS pathogens, 2020 - journals.plos.org
All symptoms of malaria disease are associated with the asexual blood stages of
development, involving cycles of red blood cell (RBC) invasion and egress by the …
development, involving cycles of red blood cell (RBC) invasion and egress by the …
Structural variation of the malaria-associated human glycophorin ABE region
S Louzada, W Algady, E Weyell, LW Zuccherato… - BMC genomics, 2020 - Springer
Background Approximately 5% of the human genome shows common structural variation,
which is enriched for genes involved in the immune response and cell-cell interactions. A …
which is enriched for genes involved in the immune response and cell-cell interactions. A …
Adaptive immunity selects against malaria infection blocking mutations
The mutation responsible for Duffy negativity, which impedes Plasmodium vivax infection,
has reached high frequencies in certain human populations. Conversely, mutations capable …
has reached high frequencies in certain human populations. Conversely, mutations capable …
High-throughput genoty** assays for identification of glycophorin B deletion variants in population studies
Glycophorins are the most abundant sialoglycoproteins on the surface of human erythrocyte
membranes. Genetic variation in glycophorin region of human chromosome 4 (containing …
membranes. Genetic variation in glycophorin region of human chromosome 4 (containing …
Antibody mediated clearance of ring-infected erythrocytes as a mechanism of protective immunity against Plasmodium falciparum malaria
FK Musasia - 2020 - archiv.ub.uni-heidelberg.de
Malaria is still a disease of global health significance. Its causative agent, Plasmodium, has
a complex lifecycle alternating between the female Anopheles mosquito and the vertebrate …
a complex lifecycle alternating between the female Anopheles mosquito and the vertebrate …
Survival strategies of host, parasite, and vector in human Malaria
FB Mandal - Researcher Bulletin of Medical Sciences, 2022 - theses.sbmu.ac.ir
Malaria, the best example of infectious protozoan diseases, has been tremendously
impacted the human genome. The global spread of malaria reflects the successful …
impacted the human genome. The global spread of malaria reflects the successful …
[PDF][PDF] African Journal of Pharmaceutical Sciences
FB Mandal - 2021 - svedbergopen.com
The global human population is perhaps at the face of an unprecedented challenge due to
the most devastative infection of a new virus, severe acute respiratory syndrome coronavirus …
the most devastative infection of a new virus, severe acute respiratory syndrome coronavirus …