Brain–immune interactions and neuroinflammation after traumatic brain injury

V Dinet, KG Petry, J Badaut - Frontiers in neuroscience, 2019 - frontiersin.org
Traumatic brain injury (TBI) is the principal cause of death and disability in children and
young adults. Clinical and preclinical research efforts have been carried out to understand …

Chronic cerebrovascular dysfunction after traumatic brain injury

A Jullienne, A Obenaus, A Ichkova… - Journal of …, 2016 - Wiley Online Library
Traumatic brain injuries (TBI) often involve vascular dysfunction that leads to long‐term
alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form …

[HTML][HTML] Traumatic brain injury imaging in the second near-infrared window with a molecular fluorophore

X Zhang, H Wang, AL Antaris, L Li, S Diao… - … (Deerfield Beach, Fla …, 2016 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide, therefore
important to understanding pathogenesis. Here, we designed a bright, renal-excreted and …

Treatment with the vascular endothelial growth factor-A antibody, bevacizumab, has sex-specific effects in a rat model of mild traumatic brain injury

M Sun, TL Baker, CT Wilson, RD Brady… - Journal of Cerebral …, 2024 - journals.sagepub.com
Mild traumatic brain injury (mTBI) involves damage to the cerebrovascular system. Vascular
endothelial growth factor-A (VEGF-A) is an important modulator of vascular health and VEGF …

Targeting the cerebrovascular system: next-generation biomarkers and treatment for mild traumatic brain injury

TL Baker, DV Agoston, RD Brady, B Major… - The …, 2022 - journals.sagepub.com
The diagnosis, prognosis, and treatment of mild traumatic brain injuries (mTBIs), such as
concussions, are significant unmet medical issues. The kinetic forces that occur in mTBI …

Early cerebrovascular and long-term neurological modifications ensue following juvenile mild traumatic brain injury in male mice

A Ichkova, B Rodriguez-Grande, E Zub, A Saudi… - Neurobiology of …, 2020 - Elsevier
Clinical evidence suggests that a mild traumatic brain injury occurring at a juvenile age
(jmTBI) may be sufficient to elicit pathophysiological modifications. However, clinical reports …

Using functional and molecular MRI techniques to detect neuroinflammation and neuroprotection after traumatic brain injury

W Wang, H Zhang, DH Lee, J Yu, T Cheng… - Brain, Behavior, and …, 2017 - Elsevier
This study was designed to investigate whether functional and molecular MRI techniques
are sensitive biomarkers for assessment of neuroinflammation and drug efficacy after …

Ultrasound, photoacoustic, and magnetic resonance imaging to study hyperacute pathophysiology of traumatic and vascular brain injury

A Kamali, LA Dieckhaus, EC Peters… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Cerebrovascular dynamics and pathomechanisms that
evolve in the minutes and hours following traumatic vascular injury in the brain remain …

Treatment with vascular endothelial growth factor-A worsens cognitive recovery in a rat model of mild traumatic brain injury

M Sun, TL Baker, CT Wilson, RD Brady… - Frontiers in Molecular …, 2022 - frontiersin.org
Mild traumatic brain injury (mTBI) is a common and unmet clinical issue, with limited
treatments available to improve recovery. The cerebrovascular system is vital to provide …

Pathophysiology of blood-brain barrier in brain injury in cold and hot environments: novel drug targets for neuroprotection

H Shanker Sharma, D F. Muresanu… - CNS & Neurological …, 2016 - benthamdirect.com
The blood-brain barrier (BBB) plays a pivotal role in the maintenance of central nervous
system function in health and disease. Thus, in almost all neurodegenerative, traumatic or …