Brain–immune interactions and neuroinflammation after traumatic brain injury
Traumatic brain injury (TBI) is the principal cause of death and disability in children and
young adults. Clinical and preclinical research efforts have been carried out to understand …
young adults. Clinical and preclinical research efforts have been carried out to understand …
Chronic cerebrovascular dysfunction after traumatic brain injury
Traumatic brain injuries (TBI) often involve vascular dysfunction that leads to long‐term
alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form …
alterations in physiological and cognitive functions of the brain. Indeed, all the cells that form …
[HTML][HTML] Traumatic brain injury imaging in the second near-infrared window with a molecular fluorophore
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide, therefore
important to understanding pathogenesis. Here, we designed a bright, renal-excreted and …
important to understanding pathogenesis. Here, we designed a bright, renal-excreted and …
Treatment with the vascular endothelial growth factor-A antibody, bevacizumab, has sex-specific effects in a rat model of mild traumatic brain injury
M Sun, TL Baker, CT Wilson, RD Brady… - Journal of Cerebral …, 2024 - journals.sagepub.com
Mild traumatic brain injury (mTBI) involves damage to the cerebrovascular system. Vascular
endothelial growth factor-A (VEGF-A) is an important modulator of vascular health and VEGF …
endothelial growth factor-A (VEGF-A) is an important modulator of vascular health and VEGF …
Targeting the cerebrovascular system: next-generation biomarkers and treatment for mild traumatic brain injury
The diagnosis, prognosis, and treatment of mild traumatic brain injuries (mTBIs), such as
concussions, are significant unmet medical issues. The kinetic forces that occur in mTBI …
concussions, are significant unmet medical issues. The kinetic forces that occur in mTBI …
Early cerebrovascular and long-term neurological modifications ensue following juvenile mild traumatic brain injury in male mice
A Ichkova, B Rodriguez-Grande, E Zub, A Saudi… - Neurobiology of …, 2020 - Elsevier
Clinical evidence suggests that a mild traumatic brain injury occurring at a juvenile age
(jmTBI) may be sufficient to elicit pathophysiological modifications. However, clinical reports …
(jmTBI) may be sufficient to elicit pathophysiological modifications. However, clinical reports …
Using functional and molecular MRI techniques to detect neuroinflammation and neuroprotection after traumatic brain injury
This study was designed to investigate whether functional and molecular MRI techniques
are sensitive biomarkers for assessment of neuroinflammation and drug efficacy after …
are sensitive biomarkers for assessment of neuroinflammation and drug efficacy after …
Ultrasound, photoacoustic, and magnetic resonance imaging to study hyperacute pathophysiology of traumatic and vascular brain injury
Abstract Background and Purpose Cerebrovascular dynamics and pathomechanisms that
evolve in the minutes and hours following traumatic vascular injury in the brain remain …
evolve in the minutes and hours following traumatic vascular injury in the brain remain …
Treatment with vascular endothelial growth factor-A worsens cognitive recovery in a rat model of mild traumatic brain injury
M Sun, TL Baker, CT Wilson, RD Brady… - Frontiers in Molecular …, 2022 - frontiersin.org
Mild traumatic brain injury (mTBI) is a common and unmet clinical issue, with limited
treatments available to improve recovery. The cerebrovascular system is vital to provide …
treatments available to improve recovery. The cerebrovascular system is vital to provide …
Pathophysiology of blood-brain barrier in brain injury in cold and hot environments: novel drug targets for neuroprotection
H Shanker Sharma, D F. Muresanu… - CNS & Neurological …, 2016 - benthamdirect.com
The blood-brain barrier (BBB) plays a pivotal role in the maintenance of central nervous
system function in health and disease. Thus, in almost all neurodegenerative, traumatic or …
system function in health and disease. Thus, in almost all neurodegenerative, traumatic or …