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Malaria: the past and the present
Malaria is a severe disease caused by parasites of the genus Plasmodium, which is
transmitted to humans by a bite of an infected female mosquito of the species Anopheles …
transmitted to humans by a bite of an infected female mosquito of the species Anopheles …
Artemisinins: pharmacological actions beyond anti-malarial
Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …
Chemotherapy of leishmaniasis: present challenges
Cutaneous and visceral leishmaniasis are amongst the most devastating infectious diseases
of our time, affecting millions of people worldwide. The treatment of these serious diseases …
of our time, affecting millions of people worldwide. The treatment of these serious diseases …
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine
Malaria inflicts an enormous burden on global human health. The emergence of parasite
resistance to front-line drugs has prompted a renewed focus on the repositioning of clinically …
resistance to front-line drugs has prompted a renewed focus on the repositioning of clinically …
Discovery, mechanisms of action and combination therapy of artemisinin
Despite great international efforts, malaria still inflicts an enormous toll on human lives,
especially in Africa. Throughout history, antimalarial medicines have been one of the most …
especially in Africa. Throughout history, antimalarial medicines have been one of the most …
Opportunities and challenges in antiparasitic drug discovery
R Pink, A Hudson, MA Mouriès, M Bendig - Nature reviews Drug …, 2005 - nature.com
New antiparasitic drugs are urgently needed to treat and control diseases such as malaria,
leishmaniasis, slee** sickness and filariasis, which affect millions of people each year …
leishmaniasis, slee** sickness and filariasis, which affect millions of people each year …
[HTML][HTML] Artemisinins: their growing importance in medicine
Artemisinins are derived from extracts of sweet wormwood (Artemisia annua) and are well
established for the treatment of malaria, including highly drug-resistant strains. Their efficacy …
established for the treatment of malaria, including highly drug-resistant strains. Their efficacy …
Tongkat Ali (Eurycoma longifolia Jack): a review on its ethnobotany and pharmacological importance
Eurycoma longifolia Jack is an herbal medicinal plant of South-East Asian origin, popularly
recognized as 'Tongkat Ali.'The plant parts have been traditionally used for its antimalarial …
recognized as 'Tongkat Ali.'The plant parts have been traditionally used for its antimalarial …
A randomised, double blind, placebo-controlled pilot study of oral artesunate therapy for colorectal cancer
Background Artesunate is an antimalarial agent with broad anti-cancer activity in in vitro and
animal experiments and case reports. Artesunate has not been studied in rigorous clinical …
animal experiments and case reports. Artesunate has not been studied in rigorous clinical …
Selective release of multiple DNA oligonucleotides from gold nanorods
Combination therapy, or the use of multiple drugs, has been proven to be effective for
complex diseases, but the differences in chemical properties and pharmacokinetics can be …
complex diseases, but the differences in chemical properties and pharmacokinetics can be …