Host-directed immunotherapy of viral and bacterial infections: past, present and future
The advent of COVID-19 and the persistent threat of infectious diseases such as
tuberculosis, malaria, influenza and HIV/AIDS remind us of the marked impact that infections …
tuberculosis, malaria, influenza and HIV/AIDS remind us of the marked impact that infections …
Tuberculosis: progress and advances in development of new drugs, treatment regimens, and host-directed therapies
Tuberculosis remains the world's leading cause of death from an infectious disease,
responsible for an estimated 1 674 000 deaths annually. WHO estimated 600 000 cases of …
responsible for an estimated 1 674 000 deaths annually. WHO estimated 600 000 cases of …
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients
Abstract Background The SARS-CoV-2 pandemic is currently leading to increasing numbers
of COVID-19 patients all over the world. Clinical presentations range from asymptomatic …
of COVID-19 patients all over the world. Clinical presentations range from asymptomatic …
Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
The Macrophage: A Disputed Fortress in the Battle against Mycobacterium tuberculosis
CJ Queval, R Brosch, R Simeone - Frontiers in microbiology, 2017 - frontiersin.org
Mycobacterium tuberculosis (Mtb), the etiological agent of human tuberculosis (TB), has
plagued humans for thousands of years. TB still remains a major public health problem in …
plagued humans for thousands of years. TB still remains a major public health problem in …
Host-directed therapies for infectious diseases: current status, recent progress, and future prospects
Despite extensive global efforts in the fight against killer infectious diseases, they still cause
one in four deaths worldwide and are important causes of long-term functional disability …
one in four deaths worldwide and are important causes of long-term functional disability …
[HTML][HTML] Human tuberculosis and Mycobacterium tuberculosis complex: A review on genetic diversity, pathogenesis and omics approaches in host biomarkers …
Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …
encompassing nine members of closely related species that causes tuberculosis in animals …
Tuberculosis—advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers
Tuberculosis is the leading infectious cause of death worldwide, with 9· 6 million cases and
1· 5 million deaths reported in 2014. WHO estimates 480 000 cases of these were multidrug …
1· 5 million deaths reported in 2014. WHO estimates 480 000 cases of these were multidrug …
Molecular determinants in phagocyte-bacteria interactions
SHE Kaufmann, A Dorhoi - Immunity, 2016 - cell.com
Phagocytes are crucial for host defense against bacterial pathogens. As first demonstrated
by Metchnikoff, neutrophils and mononuclear phagocytes share the capacity to engulf, kill …
by Metchnikoff, neutrophils and mononuclear phagocytes share the capacity to engulf, kill …
Host directed therapies for tuberculosis: futures strategies for an ancient disease
I Palucci, G Delogu - Chemotherapy, 2018 - karger.com
The emergence and spread of drug-resistant strains of Mycobacterium tuberculosis is
worsening the global threat of tuberculosis (TB). There is a need and urgency for the …
worsening the global threat of tuberculosis (TB). There is a need and urgency for the …