Molecular mechanisms of environmental exposures and human disease

H Wu, CM Eckhardt, AA Baccarelli - Nature reviews genetics, 2023 - nature.com
A substantial proportion of disease risk for common complex disorders is attributable to
environmental exposures and pollutants. An appreciation of how environmental pollutants …

Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics

L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …

Evaluation of post-translational modifications in histone proteins: A review on histone modification defects in developmental and neurological disorders

S Ramazi, A Allahverdi, J Zahiri - Journal of biosciences, 2020 - Springer
Post-translational modification (PTM) in histone proteins is a covalent modification which
mainly consists of methylation, phosphorylation, acetylation, ubiquitylation, SUMOylation …

Molecular mechanism of arsenic-induced neurotoxicity including neuronal dysfunctions

M Thakur, M Rachamalla, S Niyogi… - International Journal of …, 2021 - mdpi.com
Arsenic is a key environmental toxicant having significant impacts on human health. Millions
of people in develo** countries such as Bangladesh, Mexico, Taiwan, and India are …

[HTML][HTML] Environmental arsenic exposure: from genetic susceptibility to pathogenesis

BC Minatel, AP Sage, C Anderson, R Hubaux… - Environment …, 2018 - Elsevier
More than 200 million people in 70 countries are exposed to arsenic through drinking water.
Chronic exposure to this metalloid has been associated with the onset of many diseases …

Environmental toxicants: human exposures and their health effects

M Lippmann - 2000 - books.google.com
A comprehensive guide to assessing the health effects of environmental toxicants in
nonoccupational settings Now in a second edition, Environmental Toxicants: Human …

An expanding repertoire of protein acylations

Y Xu, Z Shi, L Bao - Molecular & Cellular Proteomics, 2022 - ASBMB
Protein post-translational modifications play key roles in multiple cellular processes by
allowing rapid reprogramming of individual protein functions. Acylation, one of the most …

Molecular mechanisms of arsenic-induced disruption of DNA repair

LM Tam, NE Price, Y Wang - Chemical research in toxicology, 2020 - ACS Publications
Exposure to arsenic in contaminated drinking water is an emerging public health problem
that impacts more than 200 million people worldwide. Accumulating lines of evidence from …

Epigenetic modifications from arsenic exposure: A comprehensive review

A Chakraborty, S Ghosh, B Biswas, S Pramanik… - Science of the total …, 2022 - Elsevier
Arsenic is a notorious element with the potential to harm exposed individuals in ways that
include cancerous and non-cancerous health complications. Millions of people across the …

Recent advances in arsenic research: significance of differential susceptibility and sustainable strategies for mitigation

T Sanyal, P Bhattacharjee, S Paul… - Frontiers in public …, 2020 - frontiersin.org
Arsenic contamination in drinking water and associated adverse outcomes are one of the
major health issues in more than 50 countries worldwide. The scenario is getting even more …