Nanomaterial-based regulation of redox metabolism for enhancing cancer therapy
X Jia, Y Wang, Y Qiao, X Jiang, J Li - Chemical Society Reviews, 2024 - pubs.rsc.org
Altered redox metabolism is one of the hallmarks of tumor cells, which not only contributes to
tumor proliferation, metastasis, and immune evasion, but also has great relevance to …
tumor proliferation, metastasis, and immune evasion, but also has great relevance to …
[HTML][HTML] Metformin-based nanomedicines for reprogramming tumor immune microenvironment
Immunotherapy has transformed current cancer management, and it has achieved
significant progress over last decades. However, an immunosuppressive tumor …
significant progress over last decades. However, an immunosuppressive tumor …
[HTML][HTML] Self-assembled PROTACs enable protein degradation to reprogram the tumor microenvironment for synergistically enhanced colorectal cancer …
Both β-catenin and STAT3 drive colorectal cancer (CRC) growth, progression, and immune
evasion, and their co-overexpression is strongly associated with a poor prognosis. However …
evasion, and their co-overexpression is strongly associated with a poor prognosis. However …
[HTML][HTML] Nano biosensors: Classification, electrochemistry, nanostructures, and optical properties
The incidence of chronic diseases in contemporary society has been steadily rising with the
ageing population. They place a significant strain on both people and the healthcare system …
ageing population. They place a significant strain on both people and the healthcare system …
Triphenylphosphine-Modified IridiumIII, RhodiumIII, and RutheniumII Complexes to Achieve Enhanced Anticancer Selectivity by Targeting Mitochondria
Z Liu, H Fu, H Dong, K Lai, Z Yang, C Fan… - Inorganic …, 2024 - ACS Publications
The incorporation of an organelle-targeting moiety into compounds has proven to be an
effective strategy in the development of targeted anticancer drugs. We herein report the …
effective strategy in the development of targeted anticancer drugs. We herein report the …
Rationale, in silico docking, ADMET profile, design, synthesis and cytotoxicity evaluations of phthalazine derivatives as VEGFR-2 inhibitors and apoptosis inducers
New phthalazine derivatives as vascular endothelial growth factor receptor-2 (VEGFR-2)
inhibitors were synthesized joined to different spacers including pyrazole, α, β-unsaturated …
inhibitors were synthesized joined to different spacers including pyrazole, α, β-unsaturated …
Bioengineering stimuli-responsive organic-inorganic nanoarchitetures based on carboxymethylcellulose-poly-l-lysine nanoplexes: Unlocking the potential for …
Regrettably, glioblastoma multiforme (GBM) remains the deadliest form of brain cancer,
where the early diagnosis plays a pivotal role in the patient's therapy and prognosis. Hence …
where the early diagnosis plays a pivotal role in the patient's therapy and prognosis. Hence …
Artificial intelligence for personalized nanomedicine; from material selection to patient outcomes
Introduction Artificial intelligence (AI) is changing the field of nanomedicine by exploring
novel nanomaterials for develo** therapies of high efficacy. AI works on larger datasets …
novel nanomaterials for develo** therapies of high efficacy. AI works on larger datasets …
[HTML][HTML] Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges
Malignant growth is expected to surpass other significant causes of death as one of the top
reasons for dismalness and mortality worldwide. According to a World Health Organization …
reasons for dismalness and mortality worldwide. According to a World Health Organization …
Smart self-transforming nano-systems for overcoming biological barrier and enhancing tumor treatment efficacy
Nanomedicines need to overcome multiple biological barriers in the body to reach the target
area. However, traditional nanomedicines with constant physicochemical properties are not …
area. However, traditional nanomedicines with constant physicochemical properties are not …