Aggregation-Induced Emission Luminogen: Role in Biopsy for Precision Medicine
Y Duo, L Han, Y Yang, Z Wang, L Wang… - Chemical …, 2024 - ACS Publications
Biopsy, including tissue and liquid biopsy, offers comprehensive and real-time physiological
and pathological information for disease detection, diagnosis, and monitoring. Fluorescent …
and pathological information for disease detection, diagnosis, and monitoring. Fluorescent …
Targeting chromosomal instability in patients with cancer
Chromosomal instability (CIN) is a hallmark of cancer and a driver of metastatic
dissemination, therapeutic resistance, and immune evasion. CIN is present in 60–80% of …
dissemination, therapeutic resistance, and immune evasion. CIN is present in 60–80% of …
A comprehensive overview of liquid biopsy applications in pediatric solid tumors
FW Janssen, NSM Lak, CY Janda, LA Kester… - NPJ precision …, 2024 - nature.com
Liquid biopsies are emerging as an alternative source for pediatric cancer biomarkers with
potential applications during all stages of patient care, from diagnosis to long-term follow-up …
potential applications during all stages of patient care, from diagnosis to long-term follow-up …
HATCHet2: clone-and haplotype-specific copy number inference from bulk tumor sequencing data
Bulk DNA sequencing of multiple samples from the same tumor is becoming common, yet
most methods to infer copy-number aberrations (CNAs) from this data analyze individual …
most methods to infer copy-number aberrations (CNAs) from this data analyze individual …
Genomic profiling of circulating tumor DNA for childhood cancers
The utility of circulating tumor DNA (ctDNA) analysis has not been well-established for
disease detection and monitoring of childhood cancers, especially leukemias. We …
disease detection and monitoring of childhood cancers, especially leukemias. We …
Simultaneous copy number alteration and single-nucleotide variation analysis in matched aqueous humor and tumor samples in children with retinoblastoma
Retinoblastoma (RB) is a childhood cancer that forms in the develo** retina of young
children; this tumor cannot be biopsied due to the risk of provoking extraocular tumor …
children; this tumor cannot be biopsied due to the risk of provoking extraocular tumor …
Recent developments in blood biomarkers in neuro-oncology
JB Foster, MP Koptyra, SJ Bagley - Current Neurology and Neuroscience …, 2023 - Springer
Abstract Purpose of Review Given the invasive and high-risk nature of brain surgery, the
need for non-invasive biomarkers obtained from the peripheral blood is greatest in tumors of …
need for non-invasive biomarkers obtained from the peripheral blood is greatest in tumors of …
Utility of genomic testing in children, adolescents, and young adults with cancer
Genomic testing can inform the diagnosis and personalize management of cancers in
children, adolescents, and young adults (CAYA). This sco** review explored the clinical …
children, adolescents, and young adults (CAYA). This sco** review explored the clinical …
From haystack to high precision: advanced sequencing methods to unraveling circulating tumor DNA mutations
TF Silva, JC Azevedo Jr, EB Teixeira… - Frontiers in Molecular …, 2024 - frontiersin.org
Identifying mutations in cancer-associated genes to guide patient treatments is essential for
precision medicine. Circulating tumor DNA (ctDNA) offers valuable insights for early cancer …
precision medicine. Circulating tumor DNA (ctDNA) offers valuable insights for early cancer …
Aqueous humor liquid biopsy as a Companion diagnostic for retinoblastoma: implications for diagnosis, prognosis, and Therapeutic options: five years of progress
Purpose To define the prospective use of the aqueous humor (AH) as a molecular
diagnostic and prognostic liquid biopsy for retinoblastoma (RB). Methods This is a …
diagnostic and prognostic liquid biopsy for retinoblastoma (RB). Methods This is a …