Mechanisms and clinical relevance of the bidirectional relationship of viral infections with metabolic diseases

N Perakakis, H Harb, BG Hale, Z Varga… - The Lancet Diabetes & …, 2023 - thelancet.com
Viruses have been present during all evolutionary steps on earth and have had a major
effect on human history. Viral infections are still among the leading causes of death. Another …

Maximizing reflexive hepatitis C virus (HCV) RNA testing of HCV antibody-reactive samples within United States public health laboratories

LN Johnson, AM Gaynor, K Wroblewski… - The Journal of …, 2024 - academic.oup.com
Hepatitis C virus (HCV) infection can have serious consequences when untreated and
diagnosis is the first step in any treatment regimen. In the Unites States a 2-step algorithm …

Peripheral immune signatures associated with the risk of hepatocarcinogenesis in cirrhotic Egyptian HCV patients before and after treatment with direct-acting …

R El-Shenawy, RI Moustafa, NM Helmy, YS El-Abd… - Virology Journal, 2024 - Springer
Background Although direct-acting antivirals (DAAs) have revolutionized the management of
chronic HCV, the debatable association with hepatocellular carcinoma (HCC) …

High-density lipoprotein cholesterol and systemic arterial hypertension are associated with hepatic necroinflammatory activity in patients with chronic hepatitis C

GHDPE Souza, LD Silva, DA Vieira… - Arquivos de …, 2023 - SciELO Brasil
Background: Approximately 71 million people are chronically infected with hepatitis C virus
(HCV) worldwide. A significant number of these individuals will develop liver cirrhosis and/or …

PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients

A Virseda-Berdices, Ó Brochado-Kith… - Frontiers in …, 2025 - frontiersin.org
Background HCV eradication with antiviral treatment reduces hepatic disease, but some
patients remain at risk of progression to cirrhosis despite HCV clearance. We aimed to …

Incident Proteinuria by Human Immunodeficiency Virus Serostatus Among Men With Pre–Diabetes Mellitus: The Multicenter AIDS Cohort Study

L Slama, BW Barrett, AG Abraham… - Clinical Infectious …, 2024 - academic.oup.com
Background Pre–diabetes mellitus (DM) is associated with proteinuria, a risk factor for
chronic kidney disease. While people living with human immunodeficiency virus (HIV; PWH) …

[HTML][HTML] Chronic Hepatitis C Infection Treated with Direct-Acting Antiviral Agents and Occurrence/Recurrence of Hepatocellular Carcinoma: Does It Still Matter?

C Smirne, MG Crobu, I Landi, N Vercellino, D Apostolo… - Viruses, 2024 - mdpi.com
Hepatitis C virus (HCV) infection is a significant risk factor for liver cirrhosis and
hepatocellular carcinoma (HCC). Traditionally, the primary prevention strategy for HCV …

[HTML][HTML] Effectiveness of direct-acting antiviral (DAA) agents on hepatitis C virus-related mixed cryoglobulinemia syndrome: One-year follow-up

HL Fayed, SM Abd El Ghany, AM Nasser… - The Egyptian …, 2023 - Elsevier
Background Mixed cryoglobulinemia syndrome (MCS) is a systemic vasculitis involving skin,
joints, kidneys, and peripheral nerves. Hepatitis C virus (HCV) is a well-known etiologic …

[HTML][HTML] Renal Manifestations of Chronic Hepatitis C: A Review

A Sohal, C Singh, A Bhalla, H Kalsi… - Journal of Clinical …, 2024 - pmc.ncbi.nlm.nih.gov
Hepatitis C virus (HCV) has emerged as a major global health concern and, if left untreated,
can lead to significant liver damage, including cirrhosis, decompensated liver disease, and …

[HTML][HTML] Role of viruses in periodontitis: An extensive review of herpesviruses, human immunodeficiency virus, coronavirus-19, papillomavirus and hepatitis viruses

MK Mahmood, MT Fatih, HA Kurda… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Periodontitis is the inflammation of the supporting structures around the dentition. Several
microbial agents, mostly bacteria, have been identified as causative factors for periodontal …