Preclinical in vivo animal models of intervertebral disc degeneration. Part 1: a systematic review

DL Poletto, JD Crowley, O Tanglay, WR Walsh… - JOR …, 2023 - Wiley Online Library
Intervertebral disc degeneration (IVDD), a widely recognized cause of lower back pain, is
the leading cause of disability worldwide. A myriad of preclinical in vivo animal models of …

A systematic review of porcine models in translational pain research

S Meijs, M Schmelz, S Meilin, W Jensen - Lab Animal, 2021 - nature.com
Translating basic pain research from rodents to humans has proven to be a challenging
task. Efforts have been made to develop preclinical large animal models of pain, such as the …

Mechanical Characterization of Non-degraded Porcine Annulus Fibrosus Material Properties

J Seifert, D Maiman, LL Frazer, A Shah… - Annals of Biomedical …, 2024 - Springer
Purpose Porcine cervical spines are commonly used as a surrogate for human lumbar
spines due to their similar anatomic and mechanical characteristics. Despite their use in …

Controversies in spine research: organ culture versus in vivo models for studies of the intervertebral disc

SN Tang, AF Bonilla, NO Chahine, AC Colbath… - JOR …, 2022 - Wiley Online Library
Intervertebral disc degeneration is a common cause of low back pain, the leading cause of
disability worldwide. Appropriate preclinical models for intervertebral disc research are …

[BOOK][B] Impactful Design: from Microfluidic Devices for Modeling the Spine to Equipment for Pandemic Relief

JP McKinley - 2023 - search.proquest.com
Lower back pain is the leading cause of physical disability worldwide. In the United States,
annual costs associated with lower back pain exceed $100 billion, as 70%-80% of …

Intervertebral disc degeneration induced by lumbar instability followed by a maintained standing posture: An in vivo rabbit model

C Chen, Y Zhao, J Liu, S Niu, M Du, S Guo, Y Chen… - 2023 - researchsquare.com
Background: Intervertebral disc degeneration (IVDD) is a major clinical cause of low back
pain. The ideal animal model should induce a degenerative process and morphological …

Низшие обезьяны как модельный объект изучения дегенеративно-дистрофических изменений позвоночника у человека

АО Оганесян, АВ Панченко… - Международный …, 2024 - vetjournal.spbguvm.ru
Аннотация Дегенеративно–дистрофические изменения позвоночника (ДДИП)–
хроническая прогрессирующая патология, характеризующаяся изменениями …