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Engineered sulfated polysaccharides for biomedical applications
Sulfated polysaccharides are ubiquitous in living systems and have central roles in
biological functions such as organism development, cell proliferation and differentiation …
biological functions such as organism development, cell proliferation and differentiation …
“Drug-Free” chitosan nanoparticles as therapeutic for cancer treatment
Chitosan is cancer cytotoxic. It induces apoptosis/necrosis/autophagy and immuno-
responses, and mitigates angiogenic and metastasis tendency of cancer cells. The lower …
responses, and mitigates angiogenic and metastasis tendency of cancer cells. The lower …
Biodegradable and biocompatible subcutaneous implants consisted of pH-sensitive mebendazole-loaded/folic acid-targeted chitosan nanoparticles for murine triple …
Background Mebendazole (MBZ) is a well-known anti-parasite drug with significant anti-
cancer properties. However, MBZ exhibits low solubility, limited absorption efficacy …
cancer properties. However, MBZ exhibits low solubility, limited absorption efficacy …
Aquaculture and its by-products as a source of nutrients and bioactive compounds
Underutilized marine resources (eg, algae, fish, and shellfish processing by-products), as
sustainable alternatives to livestock protein and interesting sources of bioactive compounds …
sustainable alternatives to livestock protein and interesting sources of bioactive compounds …
An oral bioactive chitosan-decorated doxorubicin nanoparticles/bacteria bioconjugates enhance chemotherapy efficacy in an in-situ breast cancer model
J Li, Q Wen, J Dai, B Wang, Y Lu, Z Wu, Y Fan… - International Journal of …, 2024 - Elsevier
Breast cancer is the second leading cause of cancer-related deaths among women
worldwide. Despite significant advancements in chemotherapy, its effectiveness is often …
worldwide. Despite significant advancements in chemotherapy, its effectiveness is often …
Heparanized chitosans: Towards the third generation of chitinous biomaterials
The functionalization of chitosans is an emerging research area in the design of solutions for
a wide range of biomedical applications. In particular, the modification of chitosans to …
a wide range of biomedical applications. In particular, the modification of chitosans to …
Endogenous tumor microenvironment-responsive multifunctional nanoplatforms for precision cancer theranostics
Multifunctional nanoplatforms (MFNPs) have attracted increasing attention because of their
ability to integrate diverse functional diagnostic and therapeutic agents in one system …
ability to integrate diverse functional diagnostic and therapeutic agents in one system …
Biomaterial-based responsive nanomedicines for targeting solid tumor microenvironments
Solid tumors are composed of a highly complex and heterogenic microenvironment, with
increasing metabolic status. This environment plays a crucial role in the clinical therapeutic …
increasing metabolic status. This environment plays a crucial role in the clinical therapeutic …
[HTML][HTML] Ultrasound-mediated immune regulation in tumor immunotherapy
S Sun, Q Tang, L Sun, J Zhang, L Zhang, M Xu… - Materials Today …, 2022 - Elsevier
Cancer immunotherapy, which enhances the body's immune response and inhibits immune
escape to eliminate or combat tumors, holds great promise for cancer treatment. However, it …
escape to eliminate or combat tumors, holds great promise for cancer treatment. However, it …
Overcoming therapeutic failure in osteosarcoma via Apatinib-encapsulated hydrophobic poly (ester amide) nanoparticles
Anti-angiogenic tyrosine kinase inhibitors (TKIs) have been proved to be effective in
prolonging progression-free survival in advanced osteosarcoma. However, osteosarcoma …
prolonging progression-free survival in advanced osteosarcoma. However, osteosarcoma …