This review is directed at understanding how neuronal death occurs in two distinct insults,
global ischemia and focal ischemia. These are the two principal rodent models for human …

Ischemic stroke, producing a high mortality and morbidity rate, is a common clinical disease.
Enhancing the prevention and control of ischemic stroke is particularly important. Baicalin …

Environmental enrichment (EE) and voluntary exercise (VEx) have consistently been shown
to increase adult hippocampal neurogenesis and improve spatial learning ability. Although it …

The biomedical literature on the subject of neurotrophic growth factors has expanded
prodigiously. This essay reviews neurotrophic factors (NTF) and their receptors in …

This study investigated whether positive modulators of AMPA-type glutamate receptors
influence neurotrophin expression by forebrain neurons. Treatments with the ampakine …

SIR–Alzheimer's disease (AD) is a chronic brain disorder associated with specific
pathological changes resulting in neurodegeneration and in progressive development of …

Baicalin is an important medicinal herb purified from the dry roots of Scutellaria baicalensis
Georgi. The present study was undertaken to evaluate the neuroprotective effects of baicalin …

This study tried to investigate the relationships between serum brain-derived neurotrophic
factor (BDNF) protein levels and major depressive patients and discuss the effects of …

Background During inflammation, immune cells accumulate in damaged areas and release
pro-inflammatory cytokines and neurotrophins. Brain-derived neurotrophic factor (BDNF) …

Stroke is the major cause of adult brain dysfunction. In an experimental approach to
evaluate the possible beneficial effects of administration of neurotrophic factors in stroke, we …