Reactivation and lytic replication of Kaposi's sarcoma-associated herpesvirus: an update
KK Aneja, Y Yuan - Frontiers in microbiology, 2017 - frontiersin.org
The life cycle of Kaposi's sarcoma-associated herpesvirus (KSHV) consists of two phases,
latent and lytic. The virus establishes latency as a strategy for avoiding host immune …
latent and lytic. The virus establishes latency as a strategy for avoiding host immune …
Molecular biology of KSHV lytic reactivation
Kaposi's sarcoma-associated herpesvirus (KSHV) primarily persists as a latent episome in
infected cells. During latent infection, only a limited number of viral genes are expressed that …
infected cells. During latent infection, only a limited number of viral genes are expressed that …
Mechanisms of Kaposi′ s sarcoma‐associated herpesvirus latency and reactivation
F Ye, X Lei, SJ Gao - Advances in virology, 2011 - Wiley Online Library
The life cycle of Kaposi′ s sarcoma‐associated herpesvirus (KSHV) consists of latent and
lytic replication phases. During latent infection, only a limited number of KSHV genes are …
lytic replication phases. During latent infection, only a limited number of KSHV genes are …
Towards better understanding of KSHV life cycle: from transcription and posttranscriptional regulations to pathogenesis
L Yan, V Majerciak, ZM Zheng, K Lan - Virologica Sinica, 2019 - Springer
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …
Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesis
Abstract Kaposi's Sarcoma-associated Herpesvirus (KSHV), also known as human
herpesvirus 8 (HHV-8), is the most recently identified human tumor virus, and is associated …
herpesvirus 8 (HHV-8), is the most recently identified human tumor virus, and is associated …
KSHV genome replication and maintenance
Kaposi's sarcoma associated herpesvirus (KSHV) or human herpesvirus 8 (HHV8) is a
major etiological agent for multiple severe malignancies in immune-compromised patients …
major etiological agent for multiple severe malignancies in immune-compromised patients …
Tumor viruses and cancer biology: Modulating signaling pathways for therapeutic intervention
A Saha, R Kaul, M Murakami… - Cancer biology & …, 2010 - Taylor & Francis
Tumor viruses have provided relatively simple genetic systems, which can be manipulated
for understanding the molecular mechanisms of the cellular transformation process. A …
for understanding the molecular mechanisms of the cellular transformation process. A …
Structure and function of latency-associated nuclear antigen
Latency-associated nuclear antigen (LANA) encoded by open reading frame 73 (ORF73) is
the major latent protein expressed in all forms of KSHV-associated malignancies. LANA is a …
the major latent protein expressed in all forms of KSHV-associated malignancies. LANA is a …
KSHV Rta promoter specification and viral reactivation
J Guito, DM Lukac - Frontiers in microbiology, 2012 - frontiersin.org
Viruses are obligate intracellular pathogens whose biological success depends upon
replication and packaging of viral genomes, and transmission of progeny viruses to new …
replication and packaging of viral genomes, and transmission of progeny viruses to new …
IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and …
IFI16, an innate immune DNA sensor, recognizes the nuclear episomal herpes viral
genomes and induces the inflammasome and interferon-β responses. IFI16 also regulates …
genomes and induces the inflammasome and interferon-β responses. IFI16 also regulates …