NIR fluorescence-guided tumor surgery: new strategies for the use of indocyanine green
C Egloff-Juras, L Bezdetnaya, G Dolivet… - International journal of …, 2019 - Taylor & Francis
Surgery is the frontline treatment for a large number of cancers. The objective of these
excisional surgeries is the complete removal of the primary tumor with sufficient safety …
excisional surgeries is the complete removal of the primary tumor with sufficient safety …
Multiplexed imaging for diagnosis and therapy
K Heinzmann, LM Carter, JS Lewis… - Nature Biomedical …, 2017 - nature.com
Complex molecular and metabolic phenotypes depict cancers as a constellation of different
diseases with common themes. Precision imaging of such phenotypes requires flexible and …
diseases with common themes. Precision imaging of such phenotypes requires flexible and …
Acridine orange: a review of novel applications for surgical cancer imaging and therapy
VA Byvaltsev, LA Bardonova, NR Onaka… - Frontiers in …, 2019 - frontiersin.org
Introduction: Acridine orange (AO) was first extracted from coal tar in the late nineteenth
century and was used as a fluorescent dye. In this paper, we review emergent research …
century and was used as a fluorescent dye. In this paper, we review emergent research …
Tumor treating fields increases membrane permeability in glioblastoma cells
E Chang, CB Patel, C Pohling, C Young, J Song… - Cell death …, 2018 - nature.com
Glioblastoma is the most common yet most lethal of primary brain cancers with a one-year
post-diagnosis survival rate of 65% and a five-year survival rate of barely 5%. Recently the …
post-diagnosis survival rate of 65% and a five-year survival rate of barely 5%. Recently the …
Near-infrared window II fluorescence image-guided surgery of high-grade gliomas prolongs the progression-free survival of patients
Objective: This translational study aims to investigate the clinical benefits of indocyanine
green (ICG) based near-infrared window II (NIR-II) fluorescence image-guided surgery …
green (ICG) based near-infrared window II (NIR-II) fluorescence image-guided surgery …
Phase 1 safety, pharmacokinetics, and fluorescence imaging study of tozuleristide (BLZ-100) in adults with newly diagnosed or recurrent gliomas
CG Patil, DG Walker, DM Miller, P Butte… - …, 2019 - journals.lww.com
BACKGROUND Fluorescence-guided surgery (FGS) can improve extent of resection in
gliomas. Tozuleristide (BLZ-100), a near-infrared imaging agent composed of the peptide …
gliomas. Tozuleristide (BLZ-100), a near-infrared imaging agent composed of the peptide …
3D histopathology of human tumours by fast clearing and ultramicroscopy
I Sabdyusheva Litschauer, K Becker, S Saghafi… - Scientific reports, 2020 - nature.com
Here, we describe a novel approach that allows pathologists to three-dimensionally analyse
malignant tissues, including the tumour-host tissue interface. Our visualization technique …
malignant tissues, including the tumour-host tissue interface. Our visualization technique …
Survival outcomes among patients with high-grade glioma treated with 5-aminolevulinic acid–guided surgery: A systematic review and meta-analysis
S Gandhi, A Tayebi Meybodi, E Belykh… - Frontiers in …, 2019 - frontiersin.org
Background: High-grade glioma (HGG) is associated with a dismal prognosis despite
significant advances in adjuvant therapies, including chemotherapy, immunotherapy, and …
significant advances in adjuvant therapies, including chemotherapy, immunotherapy, and …
[HTML][HTML] EGFR-targeted intraoperative fluorescence imaging detects high-grade glioma with panitumumab-IRDye800 in a phase 1 clinical trial
Q Zhou, NS van den Berg, EL Rosenthal, M Iv… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: First-line therapy for high-grade gliomas (HGGs) includes maximal safe surgical
resection. The extent of resection predicts overall survival, but current neuroimaging …
resection. The extent of resection predicts overall survival, but current neuroimaging …
VNIR–NIR hyperspectral imaging fusion targeting intraoperative brain cancer detection
Currently, intraoperative guidance tools used for brain tumor resection assistance during
surgery have several limitations. Hyperspectral (HS) imaging is arising as a novel imaging …
surgery have several limitations. Hyperspectral (HS) imaging is arising as a novel imaging …